Severe perinatal hemolytic disease due to anti-e.

Q4 Medicine
G Soler-Noda, Y Romero-Díaz, L Orbeal-Aldama, S Aquino-Rojas
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引用次数: 0

Abstract

Maternal antibody-mediated fetal red blood cell destruction secondary to non-D Rh system antibodies is a significant cause of hemolytic disease of the fetus and newborn. Here, we report a rare case of severe perinatal hemolytic disease associated with maternal antibody to the e antigen. In addition to severe anemia, the infant developed hyperbilirubinemia. Resolution of the infant's anemia and hyperbilirubinemia occurred after treatment with phototherapy, intravenous immunoglobulin, and transfusion.

Maternal antibody-mediated fetal red blood cell destruction secondary to non-D Rh system antibodies is a significant cause of hemolytic disease of the fetus and newborn. Here, we report a rare case of severe perinatal hemolytic disease associated with maternal antibody to the e antigen. In addition to severe anemia, the infant developed hyperbilirubinemia. Resolution of the infant’s anemia and hyperbilirubinemia occurred after treatment with phototherapy, intravenous immunoglobulin, and transfusion.

抗e。
母体抗体介导的胎儿红细胞破坏继发于非d Rh系统抗体是胎儿和新生儿溶血性疾病的重要原因。在这里,我们报告一个罕见的严重围产期溶血性疾病与母体抗体e抗原相关的病例。除了严重的贫血外,婴儿还出现了高胆红素血症。婴儿的贫血和高胆红素血症在光疗、静脉注射免疫球蛋白和输血治疗后得到解决。母体抗体介导的胎儿红细胞破坏继发于非d Rh系统抗体是胎儿和新生儿溶血性疾病的重要原因。在这里,我们报告一个罕见的严重围产期溶血性疾病与母体抗体e抗原相关的病例。除了严重的贫血外,婴儿还出现了高胆红素血症。婴儿的贫血和高胆红素血症在光疗、静脉注射免疫球蛋白和输血治疗后得到解决。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Immunohematology
Immunohematology Medicine-Medicine (all)
CiteScore
1.30
自引率
0.00%
发文量
18
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