Frequency of Aspirin Resistance in Ischemic Stroke Patients and Healthy Controls from Colombia.

IF 1.8 Q3 PERIPHERAL VASCULAR DISEASE

Stroke Research and Treatment Pub Date : 2021-05-21 eCollection Date: 2021-01-01 DOI:10.1155/2021/9924710

Alejandro Roman-Gonzalez, Carlos Andrés Naranjo, Walter D Cardona-Maya, Dionis Vallejo, Francisco Garcia, Cesar Franco, Leonor Alvarez, Luis Ignacio Tobón, Marta Ibeth López, Carolina Rua, Gabriel Bedoya, Ángela Cadavid, José Domingo Torres

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引用次数: 1

Abstract

Objective: To evaluate the aspirin resistance prevalence in patients with previous ischemic cerebrovascular disease undergoing aspirin therapy for secondary prevention.

Materials and methods: Three hundred fifty patients presenting ischemic strokes and 100 healthy controls under aspirin treatment were evaluated using the optic platelet aggregation test.

Results: Aspirin resistance was found in 7.4% of the patients with ischemic stroke and 4% of controls. Aspirin resistance was associated with stroke recurrence in univariate analysis (p = 0.004). Aspirin resistance was not associated with smoking, diabetes, or hypercholesterolemia.

Conclusion: Aspirin resistance is present in Colombian patients with ischemic stroke as well as in healthy controls.

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哥伦比亚缺血性脑卒中患者和健康对照者阿司匹林抵抗频率

目的:了解既往缺血性脑血管病接受阿司匹林二级预防治疗的患者的阿司匹林耐药情况。材料与方法:应用视神经血小板聚集试验对350例缺血性脑卒中患者和100例健康对照者进行阿司匹林治疗。结果:缺血性脑卒中患者出现阿司匹林抵抗的比例为7.4%，对照组为4%。单因素分析显示，阿司匹林抵抗与卒中复发相关(p = 0.004)。阿司匹林抵抗与吸烟、糖尿病或高胆固醇血症无关。结论:哥伦比亚缺血性脑卒中患者和健康对照者均存在阿司匹林抵抗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Stroke Research and Treatment PERIPHERAL VASCULAR DISEASE-

CiteScore

3.20

自引率

0.00%

发文量

审稿时长

12 weeks