Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis.

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Hypertension in Pregnancy Pub Date : 2021-08-01 Epub Date: 2021-05-17 DOI:10.1080/10641955.2021.1921792

Ahmed Arafa, Xiaowen Wang, Jia-Yi Dong, Ehab S Eshak

引用次数: 1

Abstract

Objective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE).Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The I² measured heterogeneity between studies.Results: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; I² = 0.00%).Conclusion: MS is not associated with PE.

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多发性硬化症会增加子痫前期的风险吗?系统回顾和荟萃分析。

目的:通过系统评价和荟萃分析，研究多发性硬化症(MS)是否与先兆子痫(PE)风险相关。方法:从符合条件的研究中，我们使用固定效应模型汇总MS孕妇与非MS孕妇PE的比值比(ORs)和置信区间(CIs)。I2测量了研究之间的异质性。结果:纳入8项符合条件的研究(9个队列)。与未患多发性硬化症的孕妇相比，患有多发性硬化症的孕妇没有额外的PE风险(合并OR = 0.99, 95% CI: 0.89, 1.09;i2 = 0.00%)。结论:MS与PE无相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Hypertension in Pregnancy 医学-妇产科学

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： Hypertension in Pregnancy is a refereed journal in the English language which publishes data pertaining to human and animal hypertension during gestation. Contributions concerning physiology of circulatory control, pathophysiology, methodology, therapy or any other material relevant to the relationship between elevated blood pressure and pregnancy are acceptable. Published material includes original articles, clinical trials, solicited and unsolicited reviews, editorials, letters, and other material deemed pertinent by the editors.