Multiple Enhanced Lesions in the Brain MRI of a Patient with COVID-19.

Abstract

A 67-year-old-male was hospitalised for COVID-19-associated-pneumonia on April 2, 2020. His first symptoms consisted of myalgia and a cough. COVID-19 was diagnosed based on the detection of SARS-CoV-2 viral nucleic acid through a nasopharyngeal swab specimen using real-time polymerase-chain-reaction assay. Chest computerised tomography showed patchy areas of consolidation in the peribronchial and subpleural areas of both lungs, which was consistent with COVID-19-associated-pneumonia. He had diabetes, chronic kidney disease without dialysis, and alcoholic liver disease. The patient was not a smoker, but a heavy drinker. Lopinavir/ritonavir and antibiotic therapy were initiated. On the 5th day of illness, the patient was intubated due to desaturation. On the 14th day, multi-organ failure was diagnosed, and continuous-renal-replacement-therapy and extracorporeal-membraneoxygenation were administered. On the 25th day, he was released from quarantine due to the negative results of three consecutive COVID-19-tests. He had stupor, but diffusion, and MRI showed no abnormal findings. The response was not improved until 42nd day, although sedative was not used.