Neurological pathogenesis of SARS-CoV-2 (COVID-19): from virological features to clinical symptoms.

IF 5 3区医学 Q2 IMMUNOLOGY

Inflammation and Regeneration Pub Date : 2021-05-07 DOI:10.1186/s41232-021-00165-8

Yoshitaka Kase, Hideyuki Okano

引用次数: 0

Abstract

Since the worldwide outbreak of coronavirus disease 2019 (COVID-19) in 2020, various research reports and case reports have been published. It has been found that COVID-19 causes not only respiratory disorders but also thrombosis and gastrointestinal disorders, central nervous system (CNS) disorders, and peripheral neuropathy. Compared to other disorders, there are low number of research reports and low number of summaries on COVID-19-related neural disorders. Therefore, focusing on neural disorders, we outline both basic research and clinical manifestations of COVID-19-related neural disorders.

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SARS-CoV-2（COVID-19）的神经系统发病机制：从病毒学特征到临床症状。

自 2020 年全球爆发冠状病毒病 2019（COVID-19）以来，各种研究报告和病例报告相继发表。研究发现，COVID-19不仅会导致呼吸系统疾病，还会导致血栓和胃肠道疾病、中枢神经系统（CNS）疾病和周围神经病变。与其他疾病相比，COVID-19 相关神经疾病的研究报告和摘要数量较少。因此，我们以神经系统疾病为重点，概述了 COVID-19 相关神经系统疾病的基础研究和临床表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Inflammation and Regeneration Multiple-

CiteScore

11.10

自引率

1.20%

发文量

审稿时长

11 weeks

期刊介绍： Inflammation and Regeneration is the official journal of the Japanese Society of Inflammation and Regeneration (JSIR). This journal provides an open access forum which covers a wide range of scientific topics in the basic and clinical researches on inflammation and regenerative medicine. It also covers investigations of infectious diseases, including COVID-19 and other emerging infectious diseases, which involve the inflammatory responses. Inflammation and Regeneration publishes papers in the following categories: research article, note, rapid communication, case report, review and clinical drug evaluation.