Genetic Dissection of the Erwinia amylovora Disease Cycle.

IF 9.1 1区 农林科学 Q1 PLANT SCIENCES
Annual review of phytopathology Pub Date : 2021-08-25 Epub Date: 2021-05-04 DOI:10.1146/annurev-phyto-020620-095540
Roshni R Kharadi, Jeffrey K Schachterle, Xiaochen Yuan, Luisa F Castiblanco, Jingyu Peng, Suzanne M Slack, Quan Zeng, George W Sundin
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引用次数: 16

Abstract

Fire blight, caused by the bacterial phytopathogen Erwinia amylovora, is an economically important and mechanistically complex disease that affects apple and pear production in most geographic production hubs worldwide. We compile, assess, and present a genetic outlook on the progression of an E. amylovora infection in the host. We discuss the key aspects of type III secretion-mediated infection and systemic movement, biofilm formation in xylem, and pathogen dispersal via ooze droplets, a concentrated suspension of bacteria and exopolysaccharide components. We present an overall outlook on the genetic elements contributing to E. amylovora pathogenesis, including an exploration of the impact of floral microbiomes on E. amylovora colonization, and summarize the current knowledge of host responses to an incursion and how this response stimulates further infection and systemic spread. We hope to facilitate the identification of new, unexplored areas of research in this pathosystem that can help identify evolutionarily susceptible genetic targets to ultimately aid in the design of sustainable strategies for fire blight disease mitigation.

淀粉状欧文菌病循环的遗传解剖。
火疫病是一种具有重要经济意义的、机制复杂的病害,影响着全球大多数地理生产中心的苹果和梨的生产。我们编译,评估,并提出一个遗传前景的进展淀粉样芽胞杆菌感染在宿主。我们讨论了III型分泌物介导的感染和全身运动、木质部生物膜的形成以及病原体通过软液滴(细菌和胞外多糖成分的浓缩悬浮液)传播的关键方面。我们对淀粉样芽孢杆菌发病机制的遗传因素进行了全面的展望,包括探索花微生物组对淀粉样芽孢杆菌定植的影响,并总结了宿主对入侵反应的现有知识,以及这种反应如何刺激进一步的感染和全身传播。我们希望能够促进在这一病理系统中发现新的、尚未探索的研究领域,从而帮助确定进化上易感的遗传靶点,最终帮助设计可持续的减轻火疫病的策略。
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来源期刊
Annual review of phytopathology
Annual review of phytopathology 生物-植物科学
CiteScore
16.60
自引率
1.00%
发文量
19
期刊介绍: The Annual Review of Phytopathology, established in 1963, covers major advancements in plant pathology, including plant disease diagnosis, pathogens, host-pathogen Interactions, epidemiology and ecology, breeding for resistance and plant disease management, and includes a special section on the development of concepts. The journal is now open access through Annual Reviews' Subscribe to Open program, with articles published under a CC BY license.
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