{"title":"Evaluation of antibacterial activity against <i>Candida albicans</i> according to the dosage of various denture cleansers.","authors":"Cha-Hwan Bae, Yun-Kyong Lim, Joong-Ki Kook, Mee-Kyoung Son, Yu-Ri Heo","doi":"10.4047/jap.2021.13.2.100","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to compare the antibacterial activity of currently purchasable denture cleansers against <i>Candida albicans</i>.</p><p><strong>Materials and methods: </strong>This study used tablet-type denture cleansers, Polident®, Coolingdent® and Fittydent®, along with liquid denture cleansers, Hexamedine®, Listerine® and Apple vinegar®. The antibacterial activities of denture cleansers were evaluated based on the number of <i>C. albicans</i> and concentrations of the denture cleansers.</p><p><strong>Results: </strong>In the 0.5 × 10<sup>6</sup> cfu/ml culture medium, the <i>C. albicans</i>' death rate of Polident® was significantly lower than those of Fittydent®, Hexamedine®, Listerine®, and Apple vinegar®(<i>P</i><.05). In the 0.5 × 10<sup>7</sup> cfu/, the <i>C. albicans</i>' death rates of Polident® and Coolingdent® were significantly lower than those of Fittydent®, Hexamedine®, Listerine® and Apple vinegar®(<i>P</i><.05). The <i>C. albicans</i>' death rates of Polident® and Coolingdent® were significantly decreased at 0.02 g and 0.01 g. The <i>C. albicans</i>' death rate of Fittydent® was significantly decreased at 0.005 g (<i>P</i><.05). The <i><i>C. albicans</i></i> ' death rate of Hexamedine® was significantly decreased at 1/16 dilution. The <i>C. albicans</i>' death rate of Listerine® was decreased at 1/8 dilution, and the antibacterial activity of Apple vinegar® was decreased at 1/4 dilution (<i>P</i><.05).</p><p><strong>Conclusion: </strong>As the number of <i>C. albicans</i> increased, the antibacterial activities of the denture cleansers decrease. In the tablet-type denture cleanser, all denture cleansers showed 100% <i>C. albicans</i>' death rate when used at a dose of 1 tablet. One denture cleanser showed the same antibacterial effect with only 1/3 of a tablet. In the liquid type denture cleanser, the level of dilution required was different for each denture cleanser.</p>","PeriodicalId":51291,"journal":{"name":"Journal of Advanced Prosthodontics","volume":null,"pages":null},"PeriodicalIF":2.7000,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/23/jap-13-100.PMC8110740.pdf","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Advanced Prosthodontics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4047/jap.2021.13.2.100","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/4/27 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 4
Abstract
Purpose: The purpose of this study is to compare the antibacterial activity of currently purchasable denture cleansers against Candida albicans.
Materials and methods: This study used tablet-type denture cleansers, Polident®, Coolingdent® and Fittydent®, along with liquid denture cleansers, Hexamedine®, Listerine® and Apple vinegar®. The antibacterial activities of denture cleansers were evaluated based on the number of C. albicans and concentrations of the denture cleansers.
Results: In the 0.5 × 106 cfu/ml culture medium, the C. albicans' death rate of Polident® was significantly lower than those of Fittydent®, Hexamedine®, Listerine®, and Apple vinegar®(P<.05). In the 0.5 × 107 cfu/, the C. albicans' death rates of Polident® and Coolingdent® were significantly lower than those of Fittydent®, Hexamedine®, Listerine® and Apple vinegar®(P<.05). The C. albicans' death rates of Polident® and Coolingdent® were significantly decreased at 0.02 g and 0.01 g. The C. albicans' death rate of Fittydent® was significantly decreased at 0.005 g (P<.05). The C. albicans ' death rate of Hexamedine® was significantly decreased at 1/16 dilution. The C. albicans' death rate of Listerine® was decreased at 1/8 dilution, and the antibacterial activity of Apple vinegar® was decreased at 1/4 dilution (P<.05).
Conclusion: As the number of C. albicans increased, the antibacterial activities of the denture cleansers decrease. In the tablet-type denture cleanser, all denture cleansers showed 100% C. albicans' death rate when used at a dose of 1 tablet. One denture cleanser showed the same antibacterial effect with only 1/3 of a tablet. In the liquid type denture cleanser, the level of dilution required was different for each denture cleanser.
期刊介绍:
This journal aims to convey scientific and clinical progress in the field of prosthodontics and its related areas to many dental communities concerned with esthetic and functional restorations, occlusion, implants, prostheses, and biomaterials related to prosthodontics.
This journal publishes
• Original research data of high scientific merit in the field of diagnosis, function, esthetics and stomatognathic physiology related to prosthodontic rehabilitation, physiology and mechanics of occlusion, mechanical and biologic aspects of prosthodontic materials including dental implants.
• Review articles by experts on controversies and new developments in prosthodontics.
• Case reports if they provide or document new fundamental knowledge.