Relevance of Nanotechnology in Solving Oral Drug Delivery Challenges: A Perspective Review.

IF 3 4区医学 Q2 PHARMACOLOGY & PHARMACY

Critical Reviews in Therapeutic Drug Carrier Systems Pub Date : 2020-01-01 DOI:10.1615/CritRevTherDrugCarrierSyst.2020032583

Shivsharan B Dhadde, Jagadevappa S Patil, Baburao N Chandakavathe, B S Thippeswamy, Mahantesh G Kavatekar

引用次数: 3

Abstract

Nanotechnology is opening up new opportunities in drug delivery, including oral delivery, and it may reduce toxicity and increase drug ability. Presently, researchers are expanding their knowledge in the development of oral nanomedicine to extend the scope of oral drug delivery and exhibit excellent platforms for drug transportation, target, and controlled release. The present review is an attempt to define updated oral nanostructured systems for the delivery of a wide range of drugs. The review also focuses on the use of different polymeric and other materials, technologies adopted, and benefits/drawbacks of delivery systems.

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纳米技术在解决口服给药挑战中的相关性:展望综述。

纳米技术正在为药物递送(包括口服递送)开辟新的机会，它可以降低毒性并提高药物的能力。目前，研究人员正在不断拓展口服纳米药物的开发知识，以扩大口服给药的范围，并展示出良好的药物运输、靶向和控释平台。本综述试图定义用于递送多种药物的最新口服纳米结构系统。该综述还侧重于不同聚合物和其他材料的使用，所采用的技术以及输送系统的优点/缺点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Critical Reviews in Therapeutic Drug Carrier Systems 医学-药学

CiteScore

5.50

自引率

18.50%

发文量

审稿时长

>12 weeks

期刊介绍： Therapeutic uses of a variety of drug carrier systems have significant impact on the treatment and potential cure of many chronic diseases, including cancer, diabetes mellitus, psoriasis, parkinsons, Alzheimer, rheumatoid arthritis, HIV infection, infectious diseases, asthma, and drug addiction. Scientific efforts in these areas are multidisciplinary, involving the physical, biological, medical, pharmaceutical, biological materials, and engineering fields. Articles concerning this field appear in a wide variety of journals. With the vast increase in the number of articles and the tendency to fragment science, it becomes increasingly difficult to keep abreast of the literature and to sort out and evaluate the importance and reliability of the data, especially when proprietary considerations are involved. Abstracts and noncritical articles often do not provide a sufficiently reliable basis for proper assessment of a given field without the additional perusal of the original literature. This journal bridges this gap by publishing authoritative, objective, comprehensive multidisciplinary critical review papers with emphasis on formulation and delivery systems. Both invited and contributed articles are subject to peer review.

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