Effect of mineral trioxide aggregate and biodentine™ on fracture resistance of immature teeth dentine over time: in vitro study.

Abstract

Purpose: The aim of this in vitro study was to evaluate the effect of root filling with White Mineral Trioxide Aggregate (WMTA) and Biodentine™ (BD) on the fracture resistance of simulated immature teeth over different time periods.

Methods: Sixty sound-extracted human single-rooted premolars were randomly allocated into 3 groups, 2 experimental and 1 control group, with 20 teeth each. Simulation of roots into immature apices were done using Peeso reamers. After preparation, the root canals of teeth in the experimental groups were completely filled with either WMTA or BD. The control group was subdivided into positive controls (n = 10) which received no treatment and negative controls (n = 10) which were prepared the same way and filled with normal saline. The specimens were subjected to fracture testing using a universal testing machine after 2 weeks and 3 months. The peak load to fracture and the fracture location were recorded.

Results: Regarding fracture resistance, the MTA group had the highest fracture resistance at 2 weeks testing, while at 3 months there was no significant difference between the groups (P > 0.05). Regarding fracture location, at 2 weeks there was no significant difference in the fracture location between the groups, while at 3 months, the difference was significant (P < 0.05), the middle root fracture being the most frequent (63.3%).

Conclusion: No significant difference in fracture resistant of simulated immature teeth was observed after 3 months when they were filled with Biodentine or WMTA, indicating that Biodentine could be a suitable substitute for MTA. There was no difference in the possible fracture location at 2 weeks, while after 3 months middle root fractures were more frequent.