Obsessive–compulsive symptoms in anxiety and depressive disorders: Influence of recent and/or traumatic life events

IF 5.2 3区医学 Q1 PSYCHIATRY

Revista de psiquiatria y salud mental Pub Date : 2021-10-01 DOI:10.1016/j.rpsm.2020.12.002

Arantxa Orozco , Narcís Cardoner , Cristina F. Aragón , Salvador Ruiz-Murugarren , María Vicens , Miguel Ángel Álvarez-Mon , Guillermo Lahera

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引用次数: 3

Abstract

Introduction

A high prevalence of obsessive–compulsive symptoms (OCSs) in anxiety-depressive disorders ranging from 30 to 67% has been described.

Objective

This study aims to assess the presence and persistence of OCSs in an outpatient sample of subjects with anxiety and depressive disorders, as well as its relationship with recent life events (RLEs) and/or traumatic experiences (TEs).

Method

We conducted a prospective, observational, analytical study of 200 subjects with DSM-5 diagnoses of anxiety and/or depression. Participants were included by consecutive sampling and were evaluated at baseline and after 6–12 months (mean 8.5 months) of follow-up. The severity of the symptoms was assessed through the Hamilton Anxiety Scale (HARS) and Hamilton Scale for the evaluation of depression (HRSD-17), and comorbidity was assessed through the International Neuropsychiatric Interview (MINI). The Revised Inventory of Obsessions and Compulsions (OCI-R), the Recent Vital Changes Questionnaire (CVSV), and the Diagnostic Scale for Post-Traumatic Stress (PDS) were also administered.

Results

54% of the sample presented OCSs, and 30.5% presented one or more TEs throughout life. At the baseline visit, the presence of OCSs was associated with the severity of depressive symptoms (p = 0.028), the presence of TEs (p < 0.01), symptoms of post-traumatic stress disorder (p < 0.01) and the number of RLEs (p < 0.01). Response rate at follow-up was 38%, and persistence of OCSs was found in 60.5% of patients, independent of depressive or anxious symptoms, but was associated with the number of RLEs (p < 0.01).

Conclusion

The presence of OCSs in patients with anxiety and depressive disorders is frequent and persistent. Anxious-depressive patients with a history of TEs and RLEs had higher OCS levels. These findings highlight the importance of early detection and the use of therapeutic strategies focused on resilience to stress and trauma.

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焦虑和抑郁障碍中的强迫症状:近期和/或创伤性生活事件的影响

据报道，焦虑抑郁障碍中强迫症(OCSs)的患病率很高，从30%到67%不等。目的本研究旨在评估门诊焦虑症和抑郁症患者OCSs的存在和持续性，以及其与近期生活事件(RLEs)和/或创伤经历(TEs)的关系。方法对200名DSM-5诊断为焦虑和/或抑郁的受试者进行前瞻性、观察性、分析性研究。参与者通过连续抽样纳入，并在基线和6-12个月(平均8.5个月)随访后进行评估。通过汉密尔顿焦虑量表(HARS)和汉密尔顿抑郁评估量表(HRSD-17)评估症状严重程度，通过国际神经精神病学访谈(MINI)评估合并症。同时进行强迫强迫修正量表(OCI-R)、近期生命变化问卷(CVSV)和创伤后应激诊断量表(PDS)。结果54%的患者出现过OCSs, 30.5%的患者一生中出现过一次或多次TEs。基线访视时，OCSs的存在与抑郁症状的严重程度相关(p = 0.028)， TEs的存在与抑郁症状的严重程度相关(p <0.01)，创伤后应激障碍症状(p <0.01)和RLEs数量(p <0.01)。随访有效率为38%，60.5%的患者持续存在OCSs，与抑郁或焦虑症状无关，但与RLEs次数有关(p <0.01)。结论焦虑抑郁障碍患者出现OCSs的频率和持续性较高。有TEs和RLEs病史的焦虑抑郁患者OCS水平较高。这些发现强调了早期发现和使用治疗策略的重要性，重点是对压力和创伤的恢复能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista de psiquiatria y salud mental PSYCHIATRY-

自引率

3.30%

发文量

期刊介绍： The Spanish Journal of Psychiatry and Mental Health (SJPMH), incorporated into ISSN 1888-9891, is the official scientific publication of the Spanish Society of Psychiatry and Mental Health. The journal focuses on studying mental illnesses, their pathological processes, and their psychosocial consequences, and aims to disseminate scientific advances in all areas related to mental health and illness. SJPMH accepts unpublished works on psychiatry and mental health, including their medical and social implications. The journal provides space for research in the biological, clinical, and psychosocial fields. Manuscripts undergo peer-review by external reviewers before being accepted for publication. SJPMH is indexed in Index Medicus/Medline, IBECS, Social Sciences Citation Index Journal Citation Reports/Social Sciences Edition, and Current Contents/Social and Behavioral Sciences.