Recent patents on therapeutic activities of xanthohumol: a prenylated chalconoid from hops (Humulus lupulus L.).

IF 1.8 Q3 PHARMACOLOGY & PHARMACY
Pharmaceutical patent analyst Pub Date : 2021-01-01 Epub Date: 2021-01-15 DOI:10.4155/ppa-2020-0026
Diwakar Aggarwal, Sushil K Upadhyay, Raj Singh, Hardeep S Tuli
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引用次数: 5

Abstract

There is expanding proof that specific natural compounds found in plants have additional conventional medicinal properties. One such compound is xanthohumol (XN), which is being explored as an antimicrobial, anticarcinogenic, antidiabetic and anti-inflammatory agent - aside from its utilization in dealing with conditions like autism, bone and skin improvement and microbial infections, lipid-related illnesses, and so on. XN is reported to suppress the uncontrolled production of inflammatory mediators responsible for diseases including cardiovascular disease, neurodegeneration and tumors. Further, it is accounted to limit adipogenesis and control obesity by focusing on principal adipocyte marker proteins. It is most generally utilized in the brewing industry as an additive and flavoring agent to add bitterness and aroma to beer. Present investigation sum up the patents filed in most recent 2 years on development of different pharmaceutical mixes and strategies dependent on various therapeutic potentials of XN.

黄腐酚:一种从啤酒花(Humulus lupulus L.)中提取的烯基化chalconoid。
越来越多的证据表明,在植物中发现的特定天然化合物具有额外的传统药用特性。其中一种化合物是黄腐酚(XN),除了用于治疗自闭症、骨骼和皮肤改善、微生物感染、脂质相关疾病等疾病外,它还被用作抗菌、抗癌、抗糖尿病和抗炎剂。据报道,XN可抑制导致心血管疾病、神经变性和肿瘤等疾病的炎症介质的不受控制的产生。此外,它被认为通过关注主要脂肪细胞标记蛋白来限制脂肪生成和控制肥胖。它在酿造工业中最常用作添加剂和调味剂,以增加啤酒的苦味和香气。本调查总结了近2年来根据XN的不同治疗潜力开发不同药物组合和策略的专利申请。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Pharmaceutical patent analyst
Pharmaceutical patent analyst PHARMACOLOGY & PHARMACY-
CiteScore
1.80
自引率
0.00%
发文量
22
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