Two cases of yellow urticaria revealing acute lithiasic biliary disease.

Abstract

described it as an acanthoma with features of porokeratosis, predominantly in men, on their extremeties. It is clinically described as either solitary or multiple hyperkeratotic plaques (often verrucous) or a nodule with mild pruritus. Absence of a central area of epidermal atrophy is a clinically important feature in distinguishing porokeratoma from porokeratosis. Porokeratoma is characterised by prominent multiple and confluent cornoid lamellae throughout the lesion in histopathological examination, whereas the cornoid lamellae is only located at the periphery in classical porokeratosis. The cause of porokeratoma has not been elucidated in which no family history of porokeratoma has been reported as yet. Although dermal amyloid deposits have been observed in several cases of porokeratosis, this is the first report of it occurring in porokeratoma. The causal link between the porokeratosis and the amyloidosis remains unclear. Possible treatments could include complete excision of the lesion, cryotherapy, laser or oral acitretin. It has been reported that porokeratotic cases can have malignant potential, particularly in chronic large lesions. Regular monitoring and follow-up is therefore recommended.