A preliminary study of coronavirus disease 2019 in China: the impact of cardiovascular disease on death risk.

Irene Rethemiotaki
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Abstract

Introduction: The primary purpose of this work is to study coronavirus disease 2019 (COVID-19) in China and to identify the prognostic characteristics of patients with the highest death risk.

Material and methods: The statistical methods used to derive the results of this work are the chi-square test and one-way analysis of variance (ANOVA) to examine the characteristics of COVID-19 associated deaths. A multiple logistic regression analysis was used with the odds ratio (OR) to find statistically significant prognostic factors with the highest death risk for this type of disease.

Results: According to multiple logistic regression analyses, males (OR = 1.68; 95% CI: 1.48-1.91) who are over 50 years old (OR = 7.2; 95% CI: 1.01-51.6) from Hubei (OR = 7.73; 95% CI: 5.71-10.47) have the highest risk of death from this type of disease. Moreover, individuals who are retirees (OR = 2.83; 95% CI: 2.47-3.25) and had a Wuhan-related exposure (OR = 2.17; 95% CI: 1.68-2.79) have two times higher risk of death from COVID-19, while the risk is thirteen times higher with the comorbid condition "cardiovascular disease" (OR = 13.6; 95% CI: 10.3-17.9).

Conclusions: The results of this study describe for the first time the importance of cardiovascular disease as a primary prognostic risk factor for death from coronavirus disease 2019.

Abstract Image

2019年中国冠状病毒疾病初步研究:心血管疾病对死亡风险的影响。
简介:这项工作的主要目的是研究中国的冠状病毒病2019(COVID-19),并确定死亡风险最高的患者的预后特征:这项工作的主要目的是研究中国2019年冠状病毒病(COVID-19),并确定死亡风险最高的患者的预后特征:本研究采用卡方检验和单因素方差分析(ANOVA)的统计方法来研究COVID-19相关死亡病例的特征。使用多重逻辑回归分析和几率比(OR)来寻找此类疾病死亡风险最高的具有统计学意义的预后因素:根据多重逻辑回归分析,来自湖北的 50 岁以上男性(OR = 7.2;95% CI:1.01-51.6)(OR = 7.73;95% CI:5.71-10.47)罹患此类疾病的死亡风险最高。此外,退休人员(OR = 2.83;95% CI:2.47-3.25)和与武汉有关的接触(OR = 2.17;95% CI:1.68-2.79)死于 COVID-19 的风险高出两倍,而合并 "心血管疾病 "的风险高出 13 倍(OR = 13.6;95% CI:10.3-17.9):本研究结果首次描述了心血管疾病作为2019年冠状病毒疾病死亡的主要预后风险因素的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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