{"title":"BCG Vaccine does not Protect Against COVID-19.","authors":"Mohamed F Allam, Ghada E El-D Amin","doi":"10.2174/1874306402014010045","DOIUrl":null,"url":null,"abstract":"<p><p>A recent article by Jop de Vrieze (March 23, 2020) suggested that BCG vaccine could protect against COVID-19 infections. The arguments were that several European countries, like Italy, Spain, France, and Germany, which are badly affected by COVID-19, and the USA stopped vaccination of the general population by BCG and excluded it from their routine vaccination schedule. Many people started to receive doses of BCG based on that hypothesis even before its confirmation. We think that the BCG vaccine could not protect against COVID-19 because several countries like China and Iran, which are severely affected by COVID-19, still include the BCG vaccine in its routine vaccination schedule. Other arguments include that the BCG vaccine improves cell-mediated immunity with little effect on humoral immunity; Immunity against viruses, in general, is mainly humoral.</p>","PeriodicalId":39127,"journal":{"name":"Open Respiratory Medicine Journal","volume":"14 ","pages":"45-46"},"PeriodicalIF":0.0000,"publicationDate":"2020-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705950/pdf/","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Respiratory Medicine Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874306402014010045","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 4
Abstract
A recent article by Jop de Vrieze (March 23, 2020) suggested that BCG vaccine could protect against COVID-19 infections. The arguments were that several European countries, like Italy, Spain, France, and Germany, which are badly affected by COVID-19, and the USA stopped vaccination of the general population by BCG and excluded it from their routine vaccination schedule. Many people started to receive doses of BCG based on that hypothesis even before its confirmation. We think that the BCG vaccine could not protect against COVID-19 because several countries like China and Iran, which are severely affected by COVID-19, still include the BCG vaccine in its routine vaccination schedule. Other arguments include that the BCG vaccine improves cell-mediated immunity with little effect on humoral immunity; Immunity against viruses, in general, is mainly humoral.
Jop de vrize最近发表的一篇文章(2020年3月23日)表明，卡介苗可以预防COVID-19感染。论据是，意大利、西班牙、法国和德国等受COVID-19影响严重的欧洲国家以及美国停止了对普通人群的卡介苗接种，并将其排除在常规疫苗接种计划之外。许多人甚至在该假设得到证实之前就开始接受基于该假设的卡介苗剂量。我们认为卡介苗不能预防新冠肺炎，因为中国、伊朗等疫情严重的国家仍将卡介苗纳入其常规疫苗接种计划。其他观点包括:卡介苗能改善细胞免疫，但对体液免疫影响不大;一般来说，对病毒的免疫主要是体液免疫。
期刊介绍：
The Open Respiratory Medicine Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of experimental and clinical research in respiratory medicine. Topics covered include: -COPD- Occupational disorders, and the role of allergens and pollutants- Asthma- Allergy- Non-invasive ventilation- Therapeutic intervention- Lung cancer- Lung infections respiratory diseases- Therapeutic interventions- Adult and paediatric medicine- Cell biology. The Open Respiratory Medicine Journal, a peer reviewed journal, is an important and reliable source of current information on important recent developments in the field. The emphasis will be on publishing quality articles rapidly and making them freely available worldwide.
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