The effect of topical sirolimus on superficial Kaposiform haemangioendothelioma.

Abstract

therapy for severe nephritis. This approach is similar to the KDIGO guidelines for crescentic IgA nephropathy and glomerulonephritis in antibodies-associated small vessel vasculitis. The future, however, remains bright for IgA nephropathy with emerging therapies being evaluated, including modulators of B-lymphocyte function and complement activation. Our patient’s dramatic yet unusual cutaneous presentation of vasculitis highlights the importance of screening for systemic involvement, in particular urinary sediments. Early suspicion, a careful review of clinical history, thorough evaluation, is pivotal to achieve the diagnosis before permanent end-organ damage results.