Sliding mode control for a fractional-order non-linear glucose-insulin system

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Muhammad Waleed Khan, Muhammad Abid, Abdul Qayyum Khan, Ghulam Mustafa, Muzamil Ali, Asifullah Khan
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引用次数: 10

Abstract

By providing the generalisation of integration and differentiation, and incorporating the memory and hereditary effects, fractional-order modelling has gotten significant attention in the past few years. One of the extensively studied and utilised models to describe the glucose–insulin system of a human body is Bergman's minimal model. This non-linear model comprises of integer-order differential equations. However, comparison with the experimental data shows that the fractional-order version of Bergman's minimal model is a better representative of the glucose–insulin system than its original integer-order model. To design a control law for an artificial pancreas for a diabetic patient using a fractional-order model, different techniques, including feedback linearisation, have been applied in the literature. The authors’ previous work shows that the fractional-order version of Bergman's model describes the glucose–insulin system in a better way than the integer-order model. This study applies the sliding mode control technique and then compares the obtained simulation results with the ones obtained using feedback linearisation.

Abstract Image

分数阶非线性葡萄糖-胰岛素系统的滑模控制
分数阶模型由于具有积分和微分的通用性,并结合了记忆和遗传效应,近年来得到了广泛的关注。一个被广泛研究和使用的模型来描述人体的葡萄糖-胰岛素系统是伯格曼最小模型。该非线性模型由整阶微分方程组成。然而,与实验数据的比较表明,分数阶版本的Bergman最小模型比原来的整数阶模型更能代表葡萄糖-胰岛素系统。为了使用分数阶模型设计糖尿病患者人工胰腺的控制律,文献中应用了不同的技术,包括反馈线性化。作者先前的工作表明,伯格曼模型的分数阶版本比整数阶模型更好地描述了葡萄糖-胰岛素系统。本研究采用滑模控制技术,然后将得到的仿真结果与使用反馈线性化得到的仿真结果进行比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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