Nanotechnology and stem cells in vascular biology.

Vascular biology (Bristol, England) Pub Date : 2019-09-24 eCollection Date: 2019-01-01 DOI:10.1530/VB-19-0021
Tomasz Jadczyk, Guido Caluori, Wojciech Wojakowski, Zdenek Starek
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引用次数: 0

Abstract

Nanotechnology and stem cells are one of the most promising strategies for clinical medicine applications. The article provides an up-to-date view on advances in the field of regenerative and targeted vascular therapies describing a molecular design (propulsion mechanism, composition, target identification) and applications of nanorobots. Stem cell paragraph presents current clinical application of various cell types involved in vascular biology including mesenchymal stem cells, very small embryonic-like stem cells, induced pluripotent stem cells, mononuclear stem cells, amniotic fluid-derived stem cells and endothelial progenitor cells. A possible bridging between the two fields is also envisioned, where bio-inspired, safe, long-lasting nanorobots can fully target the cellular specific cues and even drive vascular process in a timely manner.

Abstract Image

Abstract Image

血管生物学中的纳米技术和干细胞。
纳米技术和干细胞是最有希望应用于临床医学的策略之一。本文介绍了再生和靶向血管治疗领域的最新进展,描述了纳米机器人的分子设计(推进机制、组成、目标识别)和应用。干细胞部分介绍了目前血管生物学中涉及的各种细胞类型的临床应用,包括间充质干细胞、非常小的胚胎样干细胞、诱导多能干细胞、单个核干细胞、羊水来源的干细胞和内皮祖细胞。这两个领域之间可能的桥梁也被设想,生物启发的,安全的,持久的纳米机器人可以完全针对细胞的特定线索,甚至及时驱动血管过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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