Reactive Arthritis: Update.

IF 3.1 Q2 MICROBIOLOGY

Current Clinical Microbiology Reports Pub Date : 2020-01-01 Epub Date: 2020-09-26 DOI:10.1007/s40588-020-00152-6

Ibtissam Bentaleb, Kawther Ben Abdelghani, Samira Rostom, Bouchra Amine, Ahmed Laatar, Rachid Bahiri

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引用次数: 12

Abstract

Purpose of review: The aim of this paper is to provide an overview about reactive arthritis, with an update regarding pathophysiology and therapeutic approach of the disease, outlining the clinical features and diagnostic approach, based on recent literature review.

Recent findings: Reactive arthritis is considered to be part of the spectrum of the spondyloarthritis. Its epidemiology is changing worldwide due to several reasons, among them are as follows: different diagnosis approach and clinical presentations, different grades of infection, microbiome changes, etc. The understanding of pathophysiological models is challenging, but recent studies contribute to elucidate the major factors involved in the development of the disease. The management of ReA depends on the triggering agent and the phase of disease, whether it is acute or chronic.

Summary: The association between the microbiome changes and spondyloarthropathies (ReA) is becoming increasingly evident. The results regarding the biologic treatment on refectory ReA are promising.

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反应性关节炎:更新。

综述目的:本文的目的是在最近文献综述的基础上，对反应性关节炎的病理生理和治疗方法进行综述，概述其临床特征和诊断方法。最近发现:反应性关节炎被认为是脊柱炎谱系的一部分。由于不同的诊断方法和临床表现、不同的感染程度、微生物组的变化等原因，其流行病学在世界范围内正在发生变化。病理生理模型的理解是具有挑战性的，但最近的研究有助于阐明参与疾病发展的主要因素。ReA的管理取决于触发剂和疾病的阶段，无论是急性还是慢性。摘要:微生物组变化与脊椎关节病(ReA)之间的关联越来越明显。生物治疗顽固性ReA的研究结果令人看好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Clinical Microbiology Reports MICROBIOLOGY-

CiteScore

7.50

自引率

1.90%

发文量

期刊介绍： Current Clinical Microbiology Reports commissions expert reviews from leading scientists at the forefront of research in microbiology. The journal covers this broad field by dividing it into four key main areas of study: virology, bacteriology, parasitology, and mycology. Within each of the four sections, experts from around the world address important aspects of clinical microbiology such as immunology, diagnostics, therapeutics, antibiotics and antibiotic resistance, and vaccines. Some of the world’s foremost authorities in the field of microbiology serve as section editors and editorial board members. Section editors select topics for which leading researchers are invited to contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, which are highlighted in annotated reference lists. These timely reviews of the literature examine the latest scientific discoveries and controversies as they emerge and are indispensable to both researchers and clinicians. The editorial board, composed of more than 20 internationally diverse members, reviews the annual table of contents, ensures that topics address all aspects of emerging research, and where applicable suggests topics of critical importance to various countries/regions.