Limberg flap for the management of pilonidal sinus reduces disease recurrence compared to Karydakis and Bascom procedure: a systematic review and meta-analysis of randomized controlled trials.

IF 1.3 Q3 Medicine

Minerva chirurgica Pub Date : 2020-10-01 Epub Date: 2020-09-25 DOI:10.23736/S0026-4733.20.08362-5

Kausik Ray, Mohammed Albendary, Mirza K Baig, Christie Swaminathan, Parv Sains, Muhammad S Sajid

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引用次数: 3

Abstract

Introduction: The objective of this study is to compare the effectiveness of Limberg flap (LF) versus Karydakis and Bascom procedure to reduce the recurrence of pilonidal sinus disease.

Evidence acquisition: The data retrieved from the published randomized controlled trials (RCT) comparing the effectiveness of LF versus Karydakis and Bascom procedure was analyzed using the principles of meta-analysis. The summated outcome of the dichotomous data was presented in risk ratio (RR).

Evidence synthesis: Eighteen RCTs on 2073 patients comparing the effectiveness of LF versus Karydakis and or Bascom procedure for the surgical excision of pilonidal sinus disease were analyzed. In the random effects model analysis using the statistical software Review Manager 5.3, the LF was associated with the reduced risk (RR, 0.52; 95% CI: 0.29, 0.93; z=2.19; P=0.03) of disease recurrence after pilonidal sinus excision compared to Karydakis and Bascom procedure. On subgroup analysis the LF was still superior to Karidakys procedure (RR, 0.52; 95% CI: 0.23, 1.17; z=1.57; P=0.12) and Bascom procedure (RR, 0.49; 95% CI: 0.19, 1.29; z=1.44; P=0.15) but statistically it was not significant.

Conclusions: LF seems to have clinical advantage over Karydakis and Bascom procedure in terms of reduced recurrence rate following surgical excision of pilonidal sinus. Although, this advantage was clinically persisted on subgroup analysis but failed to achieve statistical significance.

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与Karydakis和Bascom手术相比，Limberg皮瓣治疗毛突窦可减少疾病复发:随机对照试验的系统回顾和荟萃分析。

前言:本研究的目的是比较Limberg皮瓣(LF)与Karydakis和Bascom手术在减少毛窦疾病复发方面的效果。证据获取:从已发表的随机对照试验(RCT)中检索数据，比较LF与Karydakis和Bascom程序的有效性，采用荟萃分析原则进行分析。风险比(RR)表示二分类数据的总和结果。证据综合:我们分析了18项随机对照试验，比较了2073例患者的LF与Karydakis和/或Bascom手术切除毛毛窦疾病的有效性。在随机效应模型分析中，使用统计软件Review Manager 5.3, LF与降低风险相关(RR, 0.52;95% ci: 0.29, 0.93;z = 2.19;P=0.03)，与Karydakis和Bascom手术相比，毛突窦切除术后疾病复发率。在亚组分析中，LF仍优于Karidakys方法(RR, 0.52;95% ci: 0.23, 1.17;z = 1.57;P=0.12)和Bascom方法(RR, 0.49;95% ci: 0.19, 1.29;z = 1.44;P=0.15)，但差异无统计学意义。结论:与Karydakis和Bascom手术相比，LF似乎在减少毛窦手术切除后的复发率方面具有临床优势。虽然在亚组分析中，这一优势在临床上持续存在，但未能达到统计学意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Minerva chirurgica 医学-外科

CiteScore

1.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Minerva Chirurgica publishes scientific papers on surgery. Manuscripts may be submitted in the form of editorials, original articles, review articles, case reports, special articles, letters to the Editor and guidelines. The journal aims to provide its readers with papers of the highest quality and impact through a process of careful peer review and editorial work.