Obesity population at risk of COVID-19 complications.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2020-11-06 eCollection Date: 2020-01-01 DOI:10.1017/gheg.2020.6

Sarah Cuschieri, Stephan Grech

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引用次数: 26

Abstract

Introduction: Global public health is challenged by two concurrent epidemics; COVID-19 and obesity. Considering the global prevalence of obesity, exploring relationships with COVID-19 are of clinical importance. The aim was to provide a comprehensive summary and recommendations on this relationship between COVID-19 and obesity.

Method: A literature search was performed to prepare a narrative review of COVID-19 and obesity.

Results: An obesity state promotes chronic inflammation, vitamin D deficiency, hinders immunity and causes mechanical lung compression. These increase susceptibilities to COVID-19 infection, complications including the requirement of invasive ventilation. Existing co-morbidities enhances these complications. Preventive measures of social distancing and self-isolation may increase stigmatisation and psychological deterrents. Hence, special recommendations targeting this vulnerable population are required.

Conclusion: The obese population is a COVID-19 vulnerable group, requiring special attention during this pandemic to avoid complications and healthcare systems burden. Lacking COVID-19 vaccination, regular physical activity and a healthy diet are recommended with attention to mental health. A prolonged quarantine duration and administration of prophylactic vitamin D may be considered.

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肥胖人群面临COVID-19并发症风险。

导言:全球公共卫生受到两大流行病的挑战;COVID-19和肥胖。考虑到全球肥胖的流行，探索与COVID-19的关系具有临床重要性。目的是就COVID-19与肥胖之间的关系提供全面的总结和建议。方法:通过文献检索，对COVID-19与肥胖的关系进行综述。结果:肥胖状态促进慢性炎症，维生素D缺乏，阻碍免疫，引起机械性肺压迫。这些增加了对COVID-19感染的易感性，并发症包括需要有创通气。现有的合并症增加了这些并发症。保持社交距离和自我隔离的预防措施可能会增加污名化和心理威慑。因此，需要针对这一弱势群体提出特别建议。结论:肥胖人群是COVID-19的弱势群体，在本次大流行期间需要特别关注，以避免并发症和卫生保健系统负担。如果没有COVID-19疫苗接种，建议定期进行身体活动和健康饮食，同时注意心理健康。可以考虑延长检疫时间并给予预防性维生素D。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.