An update on biological therapies for pediatric allergic diseases.

IF 2.6 4区 医学 Q2 Medicine
Minerva pediatrica Pub Date : 2020-10-01 Epub Date: 2020-07-20 DOI:10.23736/S0026-4946.20.05993-9
Riccardo Castagnoli, Maria De Filippo, Martina Votto, Alessia Marseglia, Lorenza Montagna, Gian Luigi Marseglia, Amelia Licari
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引用次数: 8

Abstract

Allergic diseases represent a global health burden. Patients with allergic diseases may experience disability, reduced quality of life and productivity, emotional distress, and social restrictions, especially in the most severe cases. Current advances in unveiling the pathogenesis of allergic disorders have paved the way for the development of novel therapeutic strategies. Biological drugs have been widely studied in pediatric allergic asthma, with strong evidence of efficacy and safety. Moreover, promising results derive from studies on other conditions such as atopic dermatitis, chronic spontaneous urticaria, and food allergy. This review analyzes recent evidence on the role of biologic therapies for allergic diseases, focusing on the pediatric age.

儿科变态反应性疾病生物治疗的最新进展。
过敏性疾病是全球健康负担。患有过敏性疾病的患者可能会出现残疾、生活质量和生产力下降、情绪困扰和社交限制,特别是在最严重的情况下。目前在揭示过敏性疾病的发病机制方面的进展为开发新的治疗策略铺平了道路。生物药物在儿童过敏性哮喘的治疗中得到了广泛的研究,有强有力的证据表明其有效性和安全性。此外,对特应性皮炎、慢性自发性荨麻疹和食物过敏等其他疾病的研究也取得了可喜的结果。这篇综述分析了最近的证据在生物治疗过敏性疾病的作用,重点是儿童年龄。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Minerva pediatrica
Minerva pediatrica PEDIATRICS-
CiteScore
2.70
自引率
3.80%
发文量
1
审稿时长
>12 weeks
期刊介绍: Minerva Pediatrica publishes scientific papers on pediatrics, neonatology, adolescent medicine, child and adolescent psychiatry and pediatric surgery. Manuscripts may be submitted in the form of editorials, original articles, review articles, special articles, letters to the Editor and guidelines. The journal aims to provide its readers with papers of the highest quality and impact through a process of careful peer review and editorial work.
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