Autologous full-thickness RPE-choroid graft to treat high-risk drusenoid pigment epithelial detachment without CNV.

GMS ophthalmology cases Pub Date : 2020-04-22 eCollection Date: 2020-01-01 DOI:10.3205/oc000151
Hedwig Sillen, Joke Ruys, Pieter-Paul Schauwvlieghe, Marc Veckeneer
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引用次数: 2

Abstract

Objective: To report on the survival of a retinal pigment epithelium (RPE)-choroid graft translocated to treat a patient with drusenoid pigment epithelial detachment (DPED). Methods: We describe a patient with bilateral high-risk DPED where one eye was treated with RPE-choroid translocation surgery and followed up for more than two years. Results: The RPE-choroid graft surgery was straightforward and the fully perfused graft was able to support stable vision of 0.5 Snellen acuity for more than two years despite the development of a choroidal neovessel at the edge of the graft. The vision in the fellow eye dropped from 0.5 to 0.2 Snellen in the same period. Conclusion: RPE-choroid translocation may slow the progression of DPED to atrophy but it can also transform dry age-related macular degeneration (AMD) into neovascular AMD.

自体全层rpe -脉络膜移植治疗无CNV的高危类胆色素上皮脱离。
目的:报道视网膜色素上皮(RPE)-脉络膜移植易位治疗视网膜色素上皮脱离(DPED)患者的存活情况。方法:本研究报告1例双侧高危DPED患者,单眼行rpe -脉络膜移位手术治疗,随访2年多。结果:rpe -脉络膜移植手术简单,尽管移植物边缘出现脉络膜新生血管,但充分灌注的移植物仍能维持0.5 Snellen的稳定视力两年以上。同一时期,另一只眼睛的视力从0.5斯奈伦下降到0.2斯奈伦。结论:rpe -脉络膜易位可减缓DPED向萎缩的进展,但也可使干性年龄相关性黄斑变性(AMD)转变为新生血管性AMD。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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