[Old outbreaks and new vaccines: Italy facing Ebola].

Igiene e sanita pubblica Pub Date : 2019-11-01
Elisa Terracciano, Fabiana Amadori, Laura Zaratti, Elisabetta Franco
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Abstract

Zaire is the name of the most deadly Ebola Virus (ZEBOV), which caused many outbreaks in past years and is the causative agent of the most recent one. In July 2019, Ebola was declared a public health emergency of international concern. After this declaration, the steps required to prequalify and approve the r VSV ZEBOV vaccine followed each other quickly. Nowadays in Europe the risk of an outbreak is low. However, secondary cases in USA and Spain have alerted public opinion. Italy is not involved except for the assistance to its citizens infected in countries at risk mainly in contexts of humanitarian aid. In epidemic areas the situation deserves close monitoring, as shown by the interest of the WHO, FDA and EMA. Last year the Italian Ministry of Health issued four circulars on this subject to update epidemic data and procedures and to remember precautions. The live attenuated vaccine in use now shows encouraging results; however, the need to evaluate further vaccines remains to guarantee efficacy, safety and adequate quantities.

【旧疫情和新疫苗:意大利面临埃博拉疫情】。
扎伊尔是最致命的埃博拉病毒(ZEBOV)的名称,该病毒在过去几年中引起了多次疫情,也是最近一次疫情的病原体。2019年7月,埃博拉被宣布为国际关注的突发公共卫生事件。在此声明之后,预审资格和批准VSV ZEBOV疫苗所需的步骤很快就接踵而至。如今在欧洲,疫情爆发的风险很低。然而,美国和西班牙的继发性病例引起了公众舆论的警觉。意大利不参与,但主要是在人道主义援助的情况下向在有风险的国家受感染的意大利公民提供援助。正如世卫组织、FDA和EMA的兴趣所表明的那样,疫情地区的情况值得密切监测。去年,意大利卫生部就这一问题发布了四份通告,以更新流行病数据和程序,并牢记预防措施。目前使用的减毒活疫苗显示出令人鼓舞的结果;但是,仍然需要对进一步的疫苗进行评价,以保证有效性、安全性和足够的数量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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