Prevalence of Anxiety and Depression in Prostate Cancer Patients and Their Spouses: An Unaddressed Reality.

IF 2.3 Q3 ONCOLOGY
Prostate Cancer Pub Date : 2020-01-29 eCollection Date: 2020-01-01 DOI:10.1155/2020/4393175
Ernesto Sánchez Sánchez, Antonio Carlos González Baena, Carlos González Cáliz, Fernando Caballero Paredes, José Luis Moyano Calvo, Jesús Castiñeiras Fernández
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引用次数: 12

Abstract

Objectives: To estimate the prevalence of unsuspected anxiety or depression in prostate cancer patients and their spouses, as well as factors involved in its onset. Materials and Methods. A prospective study of 184 patients and 137 spouses evaluated in our hospital during 2019 using the Memorial Anxiety Scale for Prostate Cancer (MAX-PC), Hospital Anxiety and Depression Scale (HADS) and Patient Health Questionnaire depression module (PHQ-9). This study provides an internal validity assessment of the scales and their correlation (alpha and rho coefficients; index r). The contributions of age, education level, months after diagnosis, pain, prostate-specific antigen (PSA) level, stage of the disease and treatment performed to the positivity of the questionnaires were studied using the Wilcoxon-Mann-Whitney and chi-square tests.

Results: The prevalence of anxiety was 10.9% (MAX-PC) and 28.3% (MAX-PC-PSA). The HADS-A questionnaire indicated pathology in 14.1% of the patients and 16.05% of the spouses. Depression was detected in 7% (HADS-D) and 9.2% (PHQ-9) of patients as well as in 8.8% (HADS-D) and 16.05% (PHQ-9) of their spouses. The greatest concordance between men and women was with the PHQ-9 (Spearman's rho: 0.78; p = 0.01). Education level is significantly related to the presence of anxiety and depression, regardless of the questionnaire applied. The probability of detecting pathology in the MAX-PC varied from 6% in patients with elementary education to 23.5% in university students (p = 0.04). The greatest differences were detected when applying the PHQ-9 to patients (4% pathological, elementary education vs. 35.3% pathological, university education). Our study confirms the lack of a relationship between rates of anxiety and depression and factors such as PSA level, age of the patient and number of comorbidities.

Conclusion: There is a high prevalence of unsuspected anxiety and depression in patients with prostate cancer and their wives. Education level correlates with such prevalence.

前列腺癌患者及其配偶中焦虑和抑郁的患病率:一个未解决的现实。
目的:估计前列腺癌患者及其配偶中未预料到的焦虑或抑郁的患病率,以及其发病的相关因素。材料与方法。采用前列腺癌纪念焦虑量表(MAX-PC)、医院焦虑抑郁量表(HADS)和患者健康问卷抑郁模块(PHQ-9)对2019年我院184例患者及其137对配偶进行前瞻性研究。本研究对量表及其相关系数(alpha和rho系数)进行了内部效度评估;采用Wilcoxon-Mann-Whitney检验和卡方检验研究年龄、受教育程度、诊断后数月、疼痛、前列腺特异性抗原(PSA)水平、疾病分期和治疗对问卷阳性率的影响。结果:焦虑患病率分别为10.9% (MAX-PC)和28.3% (MAX-PC- psa)。HADS-A问卷显示14.1%的患者和16.05%的配偶有病理表现。7% (HADS-D)和9.2% (PHQ-9)的患者及其配偶中有8.8% (HADS-D)和16.05% (PHQ-9)的患者存在抑郁症。男女在PHQ-9上的一致性最大(Spearman’s rho: 0.78;P = 0.01)。无论采用何种问卷,受教育程度与焦虑和抑郁的存在均显著相关。MAX-PC的病理检出率从小学教育患者的6%到大学生的23.5%不等(p = 0.04)。PHQ-9应用于患者时差异最大(病理,小学教育程度为4%,病理,大学教育程度为35.3%)。我们的研究证实,焦虑和抑郁的发生率与PSA水平、患者年龄和合并症数量等因素之间缺乏关系。结论:前列腺癌患者及其妻子存在较高的焦虑和抑郁发生率。受教育程度与这种流行程度有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Prostate Cancer
Prostate Cancer ONCOLOGY-
CiteScore
2.70
自引率
0.00%
发文量
9
审稿时长
13 weeks
期刊介绍: Prostate Cancer is a peer-reviewed, Open Access journal that provides a multidisciplinary platform for scientists, surgeons, oncologists and clinicians working on prostate cancer. The journal publishes original research articles, review articles, and clinical studies related to the diagnosis, surgery, radiotherapy, drug discovery and medical management of the disease.
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