A Single-Center Experience on Below-The-Knee Endovascular Treatment in Diabetic Patients.

IF 1.1 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
Translational Medicine at UniSa Pub Date : 2020-02-20 eCollection Date: 2020-01-01
E Dinoto, F Pecoraro, D Mirabella, F Ferlito, A Farina, N Lo Biundo, P Orlando-Conti, G Bajardi
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引用次数: 0

Abstract

Diabetic ulceration of the foot is a major global medical, social and economic problem and is the most frequent end-point of diabetic complications. A retrospective analysis from February 2017 to May 2019 of diabetic patients presenting below-the-knee artery disease (PAD) was carried out. Only patients treated with endovascular techniques as first choice treatment were evaluated. Outcome measured was perioperative mortality and morbidity. Freedom from occlusion, secondary patency and amputation rate were all registered. Additional maneuvers including stenting or angioplasty with drug eluting balloon (DEB) were reported. A total of 167 (101 male/66 female) patients with a mean age of 71 years were included in the study. A Rutherford 3, 4, 5 and 6 categories were reported in 5, 7, 110 and 45 patients, respectively. No perioperative mortality was reported. Morbidity occurred in 4 (4.4%) cases and consisted of pseudoaneurysm. Additional stenting during first procedure was required in 7 (4%) patients, drug eluting balloon was needed in 56 (33%) patients. At 1-year follow-up, estimated freedom from occlusion and secondary patency was 70% and 80% respectively. Major amputation rate was 2.4%, minor amputation rate was 41.9%. In our experience, extreme revascularization in search of distal direct flow reduce the rate of amputations with an increase in ulcer healing. New materials and techniques such as drug eluting technology, used properly, can improve outcome.

糖尿病患者膝下血管内治疗的单中心经验。
糖尿病足溃疡是一个重大的全球性医疗、社会和经济问题,也是糖尿病并发症最常见的终点。2017年2月至2019年5月期间,对出现膝下动脉疾病(PAD)的糖尿病患者进行了回顾性分析。仅对首选血管内技术治疗的患者进行了评估。衡量的结果是围手术期死亡率和发病率。此外,还记录了闭塞自由度、二次通畅率和截肢率。报告还包括支架植入术或使用药物洗脱球囊(DEB)的血管成形术。共有 167 名患者(101 名男性/66 名女性)参与了这项研究,他们的平均年龄为 71 岁。据报告,卢瑟福 3、4、5 和 6 级患者分别有 5、7、110 和 45 人。没有围手术期死亡率的报告。发病率为4例(4.4%),包括假性动脉瘤。7例(4%)患者需要在首次手术中进行额外的支架植入,56例(33%)患者需要使用药物洗脱球囊。随访1年后,估计闭塞发生率和二次通畅率分别为70%和80%。大截肢率为 2.4%,小截肢率为 41.9%。根据我们的经验,为寻求远端直接血流而进行的极端血管再通术降低了截肢率,同时提高了溃疡愈合率。正确使用药物洗脱技术等新材料和新技术可以改善治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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Translational Medicine at UniSa
Translational Medicine at UniSa MEDICINE, RESEARCH & EXPERIMENTAL-
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