Gaylen E Fronk, Sarah J Sant'Ana, Jesse T Kaye, John J Curtin
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引用次数: 0
Abstract
Clinicians and researchers alike have long believed that stressors play a pivotal etiologic role in risk, maintenance, and/or relapse of alcohol and other substance use disorders (SUDs). Numerous seminal and contemporary theories on SUD etiology posit that stressors may motivate drug use and that individuals who use drugs chronically may display altered responses to stressors. We use foundational basic stress biology research as a lens through which to evaluate critically the available evidence to support these key stress-SUD theses in humans. Additionally, we examine the field's success to date in targeting stressors and stress allostasis in treatments for SUDs. We conclude with our recommendations for how best to advance our understanding of the relationship between stressors and drug use, and we discuss clinical implications for treatment development.
长期以来,临床医生和研究人员都认为,压力因素在酒精和其他药物使用障碍(SUDs)的风险、维持和/或复发中起着关键的病因作用。关于药物滥用性失调症病因学的许多开创性理论和当代理论都认为,压力源可能会激发药物滥用,而长期使用药物的人可能会对压力源表现出改变的反应。我们以基础压力生物学研究为视角,批判性地评估现有证据,以支持这些关键的人类压力-SUD 理论。此外,我们还考察了该领域迄今为止在针对应激源和应激失衡治疗 SUD 方面取得的成功。最后,我们就如何更好地促进我们对压力源与药物使用之间关系的理解提出了建议,并讨论了对治疗开发的临床影响。
期刊介绍:
The Annual Review of Clinical Psychology is a publication that has been available since 2005. It offers comprehensive reviews on significant developments in the field of clinical psychology and psychiatry. The journal covers various aspects including research, theory, and the application of psychological principles to address recognized disorders such as schizophrenia, mood, anxiety, childhood, substance use, cognitive, and personality disorders. Additionally, the articles also touch upon broader issues that cut across the field, such as diagnosis, treatment, social policy, and cross-cultural and legal issues.
Recently, the current volume of this journal has transitioned from a gated access model to an open access format through the Annual Reviews' Subscribe to Open program. All articles published in this volume are now available under a Creative Commons Attribution License (CC BY), allowing for widespread distribution and use. The journal is also abstracted and indexed in various databases including Scopus, Science Citation Index Expanded, MEDLINE, EMBASE, CINAHL, PsycINFO, and Academic Search, among others.