A PdPt nanoparticle-decorated thiol-functionalized MOF with high peroxidase-like activity for colorimetric sensing of d-glucose and chlorophenol isomers†

Abstract

The peroxidase (POD)-like catalytic activity of various nanozymes was extensively applied in many significant fields. In this study, a thiol-functionalized MOF-loaded PdPt nanocomposite (UiO-66-(SH)₂@PdPt) was fabricated, which possesses superior and selective POD-like activity with strong affinity towards H₂O₂ and 3,3′,5,5′-tetramethylbenzidine under mild conditions. The POD-like property of UiO-66-(SH)₂@PdPt was used to sensitively detect the concentration of D-glucose under near-neutral (pH = 6.5) conditions. The detection limit of D-glucose was as low as 2.7 μM, and the linear range of D-glucose was 5–700 μM. In addition, UiO-66-(SH)₂@PdPt could accelerate the oxidative coupling chromogenic reaction of chlorophenol (CP) and 4-aminoantipyrine (4-AAP) in the presence of H₂O₂. Based on this phenomenon, a simple and visualized sensing array for the identification of chlorophenol contaminant isomers was further constructed to finally achieve the effective differentiation of three monochlorophenol isomers and six dichlorophenol isomers. Furthermore, a colorimetric detection method for 2-chlorophenol and 2,4-dichlorophenol was established. This work provides an effective means to improve the catalytic activity and selectivity of nanozymes by introducing an ideal carrier, which will be of significant value for the design of efficient nanozymes.