Evaluating driving abilities of patients under opioid treatment for chronic pain, by using the Vienna Test System and a newly released APP for smartphones (APP SafeDrive). The old and the new.

Igiene e sanita pubblica Pub Date : 2019-09-01

Luca Miceli, Rym Bednarova, Alessandro Rizzardo, Alvise Martini, Massimo Parolini, Vittorio Schweiger, Rossella Gottardo, Franco Tagliaro, Giorgio Della Rocca, Enrico Polati

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Abstract

Objective: The study compare two tests for evaluating the driving abilities of patients undergoing opioid therapy for chronic pain: the Vienna Test System (VTS), a software developed for this purpose, and a new free APP for smartphones (SafeDrive) measuring visual and auditory reaction times.

Methods: One hundred and five patients undergoing long term opioid therapy for chronic pain were enrolled. The driving abilities of study patients were evaluated using two tests, namely the Vienna test System (VTS) and the SafeDrive APP. The concordance between the two tests was evaluated through Cohen's test. In addition we evaluated the correlation between the results of both VTS and SafeDrive tests and prescribed Morphine Equivalent Doses (MEDs), sex, age and the specific drugs taken, by multivariate linear regression analysis.

Results: A statistically significant concordance (Cohen's K coefficient=0.476) was found between the SafeDrive APP and the VTS; multivariate linear regression analysis found no significant influences of dosage and type of opioid prescribed on test performances, but significant influences of sex and age.

Conclusions: The Authors found a significant correlation between VTS with SafeDrive test results. The SafeDrive APP is cheaper, easier to use and faster than VTS, and is portable and "usable on the road". Complex behavioral tasks such as driving may be severely impaired by psychoactive drugs, and consequently SafeDrive could be considered a useful portable screening tool to identify drivers with drug associated psychomotor impairment.

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通过维也纳测试系统和新发布的智能手机应用程序(APP SafeDrive)，评估阿片类药物治疗慢性疼痛患者的驾驶能力。旧的和新的。

目的:本研究比较了两种评估慢性疼痛阿片类药物治疗患者驾驶能力的测试:维也纳测试系统(VTS)，一种为此目的开发的软件，以及一种新的免费智能手机应用程序(SafeDrive)，用于测量视觉和听觉反应时间。方法:105例长期接受阿片类药物治疗的慢性疼痛患者。采用维也纳测试系统(Vienna test System, VTS)和SafeDrive APP两项测试对研究患者的驾驶能力进行评估。通过Cohen测试评估两项测试之间的一致性。此外，我们通过多元线性回归分析评估了VTS和SafeDrive测试结果与处方吗啡等效剂量(med)、性别、年龄和服用的特定药物之间的相关性。结果:SafeDrive APP与VTS具有统计学上显著的一致性(Cohen’s K系数=0.476);多元线性回归分析发现，处方阿片类药物的剂量和种类对测试成绩无显著影响，但性别和年龄对测试成绩有显著影响。结论:作者发现VTS与SafeDrive测试结果之间存在显著相关性。SafeDrive APP比VTS更便宜，更容易使用，速度更快，而且便携，“在路上可用”。复杂的行为任务，如驾驶可能会受到精神活性药物的严重损害，因此SafeDrive可以被认为是一种有用的便携式筛查工具，用于识别患有药物相关精神运动障碍的司机。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Igiene e sanita pubblica

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