Colonic Wall Thickening Reported in Abdominal CT: Does It Always Imply Malignancy?

IF 2 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY
Gastroenterology Research and Practice Pub Date : 2019-12-22 eCollection Date: 2019-01-01 DOI:10.1155/2019/2492097
A Akbas, H Bakir, M F Dasiran, H Dagmura, E Daldal, Z Ozsoy, Z Ozmen, O Demir, I Okan
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引用次数: 7

Abstract

Aim/background: Early diagnosis of patients with colon cancer is one of the most important parameters affecting the survival of patients. In this study, we aimed to examine the effect of the age, hemoglobin (Hb), albumin, neutrophil lymphocyte ratio (NLR), thrombocyte lymphocyte ratio (PLR), and mean platelet values (MPV) on the separation of benign and malignant diseases in patients with suspected colon wall thickness (CWT) observed in abdominal computed tomography (CT) examination.

Method: The study included 116 patients between the ages of 18 and 95 who had CT examination where the colon wall could be evaluated and who also had colonoscopy. Patients suspected for CWT in CT with difficulties in differential diagnosis were divided into two groups according to colonoscopic-histopathological evaluations. Normal or benign pathological causes were included in the first group, while malignant causes constituted the second group. Whether the two groups differed in terms of CWT, Hb, age, albumin, NLR, PLR, and MPV values was investigated with descriptive statistics.

Results: One hundred and sixteen patients (74 males, 42 females) with CT examinations and colonoscopic sampling were included in the study. After colonoscopic and histopathological evaluations, there were 64 cases in the first group and 52 in the second group. According to the results of the univariate analysis and multivariate logistic regression, CWT, Hb, NLR, and MPV were identified to be independent variables for determining colon cancer.

Conclusion: A combined evaluation of Hb, NLR, and MPV values in patients with CWT in abdominal CT examination may contribute to the separation of benign and malignant pathologies.

Abstract Image

Abstract Image

腹部CT显示的结肠壁增厚是否总是恶性肿瘤?
目的/背景:结肠癌患者的早期诊断是影响患者生存的最重要参数之一。本研究旨在探讨年龄、血红蛋白(Hb)、白蛋白、中性粒细胞淋巴细胞比(NLR)、血小板淋巴细胞比(PLR)、血小板平均值(MPV)对腹部计算机断层扫描(CT)检查疑似结肠壁厚(CWT)患者良恶性疾病分离的影响。方法:116例年龄在18岁至95岁之间的患者,均行CT检查,可评估肠壁,并行结肠镜检查。根据结肠镜-组织病理学评价,将CT怀疑为CWT且鉴别诊断困难的患者分为两组。第一组为正常或良性病理原因,第二组为恶性病理原因。采用描述性统计分析两组患者在CWT、Hb、年龄、白蛋白、NLR、PLR、MPV值方面是否存在差异。结果:116例患者(男74例,女42例)经CT检查和结肠镜检查纳入研究。经结肠镜及组织病理学检查,第一组64例,第二组52例。根据单因素分析和多因素logistic回归结果,确定CWT、Hb、NLR和MPV为判断结肠癌的自变量。结论:腹腔CT检查CWT患者的Hb、NLR和MPV值的综合评估有助于区分良恶性病变。
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来源期刊
Gastroenterology Research and Practice
Gastroenterology Research and Practice GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.40
自引率
0.00%
发文量
91
审稿时长
1 months
期刊介绍: Gastroenterology Research and Practice is a peer-reviewed, Open Access journal which publishes original research articles, review articles and clinical studies based on all areas of gastroenterology, hepatology, pancreas and biliary, and related cancers. The journal welcomes submissions on the physiology, pathophysiology, etiology, diagnosis and therapy of gastrointestinal diseases. The aim of the journal is to provide cutting edge research related to the field of gastroenterology, as well as digestive diseases and disorders. Topics of interest include: Management of pancreatic diseases Third space endoscopy Endoscopic resection Therapeutic endoscopy Therapeutic endosonography.
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