Psychosocial Stressors and Telomere Length: A Current Review of the Science.

IF 21.4 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Kelly E Rentscher, Judith E Carroll, Colter Mitchell
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引用次数: 64

Abstract

A growing literature suggests that exposure to adverse social conditions may accelerate biological aging, offering one mechanism through which adversity may increase risk for age-related disease. As one of the most extensively studied biological markers of aging, telomere length (TL) provides a valuable tool to understand potential influences of social adversity on the aging process. Indeed, a sizeable literature now links a wide range of stressors to TL across the life span. The aim of this article is to review and evaluate this extant literature with a focus on studies that investigate psychosocial stress exposures and experiences in early life and adulthood. We conclude by outlining potential biological and behavioral mechanisms through which psychosocial stress may influence TL, and we discuss directions for future research in this area.

社会心理压力源与端粒长度:最新科学综述。
越来越多的文献表明,暴露于不利的社会条件可能会加速生物衰老,这提供了逆境可能增加与年龄相关疾病风险的一种机制。作为研究最广泛的衰老生物学标志物之一,端粒长度(TL)为了解社会逆境对衰老过程的潜在影响提供了有价值的工具。事实上,现在有相当多的文献将一生中各种各样的压力源与TL联系起来。本文的目的是回顾和评估现有的文献,重点研究早期生活和成年期的社会心理压力暴露和经历。最后,我们概述了社会心理压力可能影响TL的潜在生物学和行为机制,并讨论了该领域未来的研究方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Annual Review of Public Health
Annual Review of Public Health 医学-公共卫生、环境卫生与职业卫生
CiteScore
26.60
自引率
1.40%
发文量
36
审稿时长
>12 weeks
期刊介绍: The Annual Review of Public Health has been a trusted publication in the field since its inception in 1980. It provides comprehensive coverage of important advancements in various areas of public health, such as epidemiology, biostatistics, environmental health, occupational health, social environment and behavior, health services, as well as public health practice and policy. In an effort to make the valuable research and information more accessible, the current volume has undergone a transformation. Previously, access to the articles was restricted, but now they are available to everyone through the Annual Reviews' Subscribe to Open program. This open access approach ensures that the knowledge and insights shared in these articles can reach a wider audience. Additionally, all the published articles are licensed under a CC BY license, allowing users to freely use, distribute, and build upon the content, while giving appropriate credit to the original authors.
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