{"title":"Serum magnesium concentrations in vitiligo patients.","authors":"M R Namazi, Farnoosh Nozari, Peyman Jafari","doi":"10.1684/mrh.2019.0450","DOIUrl":null,"url":null,"abstract":"<p><p>Hypomagnesemia has been shown to contribute to oxidative stress and inflammation. This study was designed to evaluate the serum magnesium (Mg) concentration in vitiligo patients versus controls. Twenty-seven patients with vitiligo were enrolled in this study, along with 27 age and sex-matched healthy controls. The mean serum Mg concentrations in the case and control groups were 0.75 ± 0.07 and 0.77 ± 0.07 mmol/L, respectively. No significant difference in the mean concentrations of Mg between the two groups was noted (P = 0.95). However, interestingly, we noticed a positive correlation between serum Mg concentration and Vitiligo Area Severity Index (VASI) score as well as the total body surface area (TBSA) concerned by the disease. Further research on the role of Mg in vitiligo is therefore warranted.</p>","PeriodicalId":18159,"journal":{"name":"Magnesium research","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Magnesium research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1684/mrh.2019.0450","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Hypomagnesemia has been shown to contribute to oxidative stress and inflammation. This study was designed to evaluate the serum magnesium (Mg) concentration in vitiligo patients versus controls. Twenty-seven patients with vitiligo were enrolled in this study, along with 27 age and sex-matched healthy controls. The mean serum Mg concentrations in the case and control groups were 0.75 ± 0.07 and 0.77 ± 0.07 mmol/L, respectively. No significant difference in the mean concentrations of Mg between the two groups was noted (P = 0.95). However, interestingly, we noticed a positive correlation between serum Mg concentration and Vitiligo Area Severity Index (VASI) score as well as the total body surface area (TBSA) concerned by the disease. Further research on the role of Mg in vitiligo is therefore warranted.
期刊介绍：
Magnesium Research, the official journal of the international Society for the Development of Research on Magnesium (SDRM), has been the benchmark journal on the use of magnesium in biomedicine for more than 30 years.
This quarterly publication provides regular updates on multinational and multidisciplinary research into magnesium, bringing together original experimental and clinical articles, correspondence, Letters to the Editor, comments on latest news, general features, summaries of relevant articles from other journals, and reports and statements from national and international conferences and symposiums.
Indexed in the leading medical databases, Magnesium Research is an essential journal for specialists and general practitioners, for basic and clinical researchers, for practising doctors and academics.
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