Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions.

IF 3.1 Q2 ONCOLOGY

Oncology Reviews Pub Date : 2019-11-28 eCollection Date: 2019-07-22 DOI:10.4081/oncol.2019.433

Rachel A Fayne, Francisco I Macedo, Steven E Rodgers, Mecker G Möller

引用次数: 10

Abstract

Sentinel lymph node (SLN) biopsy has become the standard of care for lymph node staging in melanoma and the most important predictor of survival in clinically node-negative disease. Previous guidelines recommend completion lymph node dissection (CLND) in cases of positive SLN; however, the lymph nodes recovered during CLND are only positive in a minority of these cases. Recent evidence suggests that conservative management (i.e. observation) has similar outcomes compared to CLND. We sought to review the most current literature regarding the management of SLN in metastatic melanoma and to discuss potential future directions.

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黑色素瘤中阳性区域淋巴结的演变管理:过去，现在和未来的方向。

前哨淋巴结(SLN)活检已成为黑素瘤淋巴结分期的标准护理，也是临床上淋巴结阴性疾病中最重要的生存预测指标。以前的指南建议在SLN阳性的病例中进行完全淋巴结清扫(CLND);然而，在CLND期间恢复的淋巴结仅在少数病例中呈阳性。最近的证据表明，与CLND相比，保守治疗(即观察)具有相似的结果。我们试图回顾关于SLN在转移性黑色素瘤中的治疗的最新文献，并讨论潜在的未来方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oncology Reviews ONCOLOGY-

CiteScore

6.30

自引率

0.00%

发文量

审稿时长

9 weeks

期刊介绍： Oncology Reviews is a quarterly peer-reviewed, international journal that publishes authoritative state-of-the-art reviews on preclinical and clinical aspects of oncology. The journal will provide up-to-date information on the latest achievements in different fields of oncology for both practising clinicians and basic researchers. Oncology Reviews aims at being international in scope and readership, as reflected also by its Editorial Board, gathering the world leading experts in both pre-clinical research and everyday clinical practice. The journal is open for publication of supplements, monothematic issues and for publishing abstracts of scientific meetings; conditions can be obtained from the Editor-in-Chief or the publisher.