One-Year Follow-Up Results From the Observational, Multicenter, Prospective, and Controlled Registry: The WALTZ All-Comers Study.

IF 2.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Clinical Medicine Insights. Cardiology Pub Date : 2019-06-27 eCollection Date: 2019-01-01 DOI:10.1177/1179546819854059
Alfredo E Rodriguez, Miguel Larribau, Carlos Fernandez-Pereira, Jorge Iravedra, Omar Santaera, Carlos Haiek, Juan Lloberas, Mario Montoya, Elias Sisu, Marcelo Menendez, Hernan Pavlovsky, Alfredo M Rodriguez-Granillo, Juan Mieres, Graciela Romero, Zheng Ming, William Pan, David Antoniucci
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引用次数: 2

Abstract

The aim of this study was to evaluate 1-year follow-up results in an all "comers" population treated with a new cobalt chromium bare-metal stent (BMS) design. Since August 2016 to March 2017, 201 (9.7% of screening population) consecutive patients undergoing coronary stent implantation in 11 centers in Argentina were prospectively included in our registry. The inclusion criteria were multiple-vessel disease and/or unprotected left main disease, acute coronary syndromes (ACS) with at least one severe (⩾70%) stenosis in any of major epicardial vessel. In-stent restenosis, protected left main stenosis, or impossibility to receive dual-antiplatelet therapy was an exclusion criterion. Major adverse cardiac events (MACE) were the primary endpoint and included cardiac death, myocardial infarction (MI), and target lesion revascularization (TLR); also, all components of the primary endpoint were separately analyzed. Completeness of revascularization was analyzed as post hoc data using residual SYNTAX or ERACI risk scores. Demographic characteristics showed that 6.5% of patients were very elderly, 22.5% have diabetes, 47% have multiple-vessel disease, 67% have ACS, and 32% have ST elevation MI. At a mean of 376 ± 18.1 days of follow-up, MACE was observed in 10.4% of patients: death + MI + cardiovascular accident (CVA) in 3% (6 of 201) and cardiac death + MI + CVA in 1.5% (3 of 201). Residual ERACI score ⩽5 was associated with 98% of event-free survival (P < .04). In conclusion, this prospective, multicenter, and observational all-comers registry with this novel BMS design showed a low incidence of adverse events at 1 year mainly due to coronary restenosis.

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来自观察性、多中心、前瞻性和对照注册的一年随访结果:华尔兹所有患者研究。
本研究的目的是评估使用新型钴铬裸金属支架(BMS)治疗的所有“患者”1年随访结果。自2016年8月至2017年3月,阿根廷11个中心201例(占筛查人群的9.7%)连续接受冠状动脉支架植入术的患者前瞻性纳入我们的登记。纳入标准是多血管疾病和/或无保护的左主干疾病,急性冠状动脉综合征(ACS),在任何主要心外膜血管中至少有一个严重(大于或小于70%)狭窄。排除标准为支架内再狭窄、保护性左主干狭窄或无法接受双重抗血小板治疗。主要心脏不良事件(MACE)是主要终点,包括心源性死亡、心肌梗死(MI)和靶病变血运重建术(TLR);此外,对主要终点的所有组成部分进行单独分析。使用残差SYNTAX或ERACI风险评分作为事后数据分析血运重建的完整性。人口统计学特征显示,6.5%的患者非常高龄,22.5%的患者患有糖尿病,47%的患者患有多血管疾病,67%的患者患有ACS, 32%的患者患有ST段抬高型心肌梗死。在平均376±18.1天的随访中,10.4%的患者出现MACE:死亡+心肌梗死+心血管事故(CVA)占3%(201例中6例),心源性死亡+心肌梗死+ CVA占1.5%(201例中3例)。剩余ERACI评分≥5与98%的无事件生存率相关(P
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来源期刊
Clinical Medicine Insights. Cardiology
Clinical Medicine Insights. Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
5.20
自引率
3.30%
发文量
16
审稿时长
8 weeks
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