Michael K Georgieff, Nancy F Krebs, Sarah E Cusick
{"title":"The Benefits and Risks of Iron Supplementation in Pregnancy and Childhood.","authors":"Michael K Georgieff, Nancy F Krebs, Sarah E Cusick","doi":"10.1146/annurev-nutr-082018-124213","DOIUrl":null,"url":null,"abstract":"<p><p>Iron deficiency is the most common micronutrient deficiency in the world and disproportionately affects pregnant women and young children. Iron deficiency has negative effects on pregnancy outcomes in women and on immune function and neurodevelopment in children. Iron supplementation programs have been successful in reducing this health burden. However, iron supplementation of iron-sufficient individuals is likely not necessary and may carry health risks for iron-sufficient and potentially some iron-deficient populations. This review considers the physiology of iron as a nutrient and how this physiology informs decision-making about weighing the benefits and risks of iron supplementation in iron-deficient, iron-sufficient, and iron-overloaded pregnant women and children.</p>","PeriodicalId":8009,"journal":{"name":"Annual review of nutrition","volume":null,"pages":null},"PeriodicalIF":12.6000,"publicationDate":"2019-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-nutr-082018-124213","citationCount":"83","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annual review of nutrition","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1146/annurev-nutr-082018-124213","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/5/15 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 83
Abstract
Iron deficiency is the most common micronutrient deficiency in the world and disproportionately affects pregnant women and young children. Iron deficiency has negative effects on pregnancy outcomes in women and on immune function and neurodevelopment in children. Iron supplementation programs have been successful in reducing this health burden. However, iron supplementation of iron-sufficient individuals is likely not necessary and may carry health risks for iron-sufficient and potentially some iron-deficient populations. This review considers the physiology of iron as a nutrient and how this physiology informs decision-making about weighing the benefits and risks of iron supplementation in iron-deficient, iron-sufficient, and iron-overloaded pregnant women and children.
期刊介绍：
Annual Review of Nutrition
Publication History:In publication since 1981
Scope:Covers significant developments in the field of nutrition
Topics Covered Include:
Energy metabolism;
Carbohydrates;
Lipids;
Proteins and amino acids;
Vitamins;
Minerals;
Nutrient transport and function;
Metabolic regulation;
Nutritional genomics;
Molecular and cell biology;
Clinical nutrition;
Comparative nutrition;
Nutritional anthropology;
Nutritional toxicology;
Nutritional microbiology;
Epidemiology;
Public health nutrition
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
