Renal Sympathetic Denervation in Patients with Resistant Hypertension: A Feasibility Study.

IF 7.3 Q1 PERIPHERAL VASCULAR DISEASE
Pulse Pub Date : 2019-04-01 Epub Date: 2018-07-25 DOI:10.1159/000490620
Kazuomi Kario, Jose Ramon Rumoroso, Yukie Okawara, Armando Pérez de Prado, Eulogio Garcia Fernandez, Hideaki Kagitani, Francisco Javier Goicolea Gómez, Oriol Rodríguez Leor, Goran Stankovic
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引用次数: 3

Abstract

Background/aims: We assessed the feasibility of renal sympathetic denervation (RDN) treatment in patients with resistant hypertension using the Iberis® RDN system. This study was a prospective, multicenter, single-arm feasibility registry.

Methods: We collected data from patients who underwent RDN treatment using the Iberis system. From November 2014 to February 2016, 16 patients from 6 centers in Europe were enrolled in this registry.

Results: Consistent reductions in the 24-h systolic blood pressure (SBP) and diastolic blood pressure were obtained. At any follow-up point, more than 70% of the patients were responders. The change in the 24-h SBP at 1 month was strongly correlated with that at 12 months.

Conclusion: The Iberis system is safe and effective in patients for the treatment of resistant hypertension. Furthermore, our results suggest that we can estimate the effect of RDN in the long term at the 1-month follow-up point using the 24-h SBP.

Abstract Image

Abstract Image

顽固性高血压患者肾交感神经去支配的可行性研究。
背景/目的:我们评估了使用Iberis®RDN系统对顽固性高血压患者进行肾交感神经去支配(RDN)治疗的可行性。本研究是一项前瞻性、多中心、单组可行性注册研究。方法:我们收集了使用Iberis系统接受RDN治疗的患者的数据。2014年11月至2016年2月,来自欧洲6个中心的16名患者入组。结果:24小时收缩压(SBP)和舒张压持续降低。在任何随访点,超过70%的患者有反应。1个月时24小时收缩压的变化与12个月时的变化密切相关。结论:Iberis系统治疗顽固性高血压安全有效。此外,我们的研究结果表明,我们可以使用24小时收缩压在随访1个月时评估RDN的长期影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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