Predictors and management of intravenous immunoglobulin-resistant Kawasaki disease.

Korean Journal of Pediatrics Pub Date : 2019-04-01 Epub Date: 2019-03-15 DOI:10.3345/kjp.2019.00150

Min Seob Song

引用次数: 13

Abstract

Kawasaki disease (KD) is a systemic vasculitis that mainly affects younger children. Intravenous immunoglobulin (IVIG) resistant cases are at increasing risk for coronary artery complications. The strategy on prediction of potential nonresponders and treatment of IVIG-resistant patients is now controversial. In this review the definition and predictors of IVIG-resistant KD and current evidence to guide management are discussed.

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静脉免疫球蛋白抵抗性川崎病的预测因素和治疗。

川崎病(Kawasaki disease, KD)是一种主要影响幼儿的全身性血管炎。静脉注射免疫球蛋白(IVIG)耐药病例发生冠状动脉并发症的风险增加。预测潜在无反应和治疗ivig耐药患者的策略目前存在争议。本文综述了抗ivig KD的定义和预测因素，以及指导管理的现有证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Korean Journal of Pediatrics

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Korean J Pediatr covers clinical and research works relevant to all aspects of child healthcare. The journal aims to serve pediatricians through the prompt publication of significant advances in any field of pediatrics and to rapidly disseminate recently updated knowledge to the public. Additionally, it will initiate dynamic, international, academic discussions concerning the major topics related to pediatrics. Manuscripts are categorized as review articles, original articles, and case reports. Areas of specific interest include: Growth and development, Neonatology, Pediatric neurology, Pediatric nephrology, Pediatric endocrinology, Pediatric cardiology, Pediatric allergy, Pediatric pulmonology, Pediatric infectious diseases, Pediatric immunology, Pediatric hemato-oncology, Pediatric gastroenterology, Nutrition, Human genetics, Metabolic diseases, Adolescence medicine, General pediatrics.