Primary Aldosteronism: Novel Insights.

IF 1.5 Q3 PERIPHERAL VASCULAR DISEASE
Konstantinos Stavropoulos, Konstantinos Imprialos, Vasilios Papademetriou, Charles Faselis, Kostas Tsioufis, Kyriakos Dimitriadis, Michael Doumas
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引用次数: 9

Abstract

Background: Primary aldosteronism is one of the most common causes of secondary hypertension. Patients with this endocrine syndrome are at increased cardiovascular risk, higher than hypertensive individuals with equal blood pressure levels.

Objectives: The study aimed to thoroughly present and critically discuss the novel insights into the field of primary aldosteronism, focusing on the clinically meaningful aspects.

Method: We meticulously evaluated existing data in the field of primary aldosteronism in order to summarize future perspectives in this narrative review.

Results: Novel data suggests that a subclinical form of primary aldosteronism might exist. Interesting findings might simplify the diagnostic procedure of the disease, especially for the localization of primary aldosteronism. The most promising progress has been noted in the field of the molecular basis of the disease, suggesting new potential therapeutic targets.

Conclusion: Several significant aspects are at early stages of evaluation. Future research is essential to investigate these well-promising perspectives.

原发性醛固酮增多症:新见解。
背景:原发性醛固酮增多症是继发性高血压最常见的原因之一。患有这种内分泌综合征的患者患心血管疾病的风险增加,高于血压水平相同的高血压患者。目的:本研究旨在全面呈现和批判性地讨论原发性醛固酮增多症领域的新见解,重点关注临床意义方面。方法:我们仔细评估了原发性醛固酮增多症领域的现有资料,以总结本叙事综述的未来前景。结果:新的数据表明原发性醛固酮增多症可能存在亚临床形式。有趣的发现可能简化疾病的诊断程序,特别是原发性醛固酮增多症的定位。最有希望的进展是在疾病的分子基础领域,提出了新的潜在治疗靶点。结论:几个重要方面处于早期评估阶段。未来的研究对于调查这些前景良好的观点至关重要。
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来源期刊
Current Hypertension Reviews
Current Hypertension Reviews PERIPHERAL VASCULAR DISEASE-
CiteScore
4.80
自引率
0.00%
发文量
26
期刊介绍: Current Hypertension Reviews publishes frontier reviews/ mini-reviews, original research articles and guest edited thematic issues on all the latest advances on hypertension and its related areas e.g. nephrology, clinical care, and therapy. The journal’s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all clinicians and researchers in the field of hypertension.
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