Combined transcranial and trans-spinal direct current stimulation in chronic headache: A feasibility and safety trial for a novel intervention

IF 0.9 Q4 REHABILITATION

Hong Kong Physiotherapy Journal Pub Date : 2017-12-01 DOI:10.1016/j.hkpj.2016.11.001

Ghufran Alhassani B.Med.Sc (Hons) , Julia Treleaven PhD , Siobhan S.M. Schabrun PhD

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引用次数: 11

Abstract

Background

Chronic primary headache disorders are associated with frequent, severe pain and significant functional impairment, with treatment remaining challenging.

Objective

We examined the feasibility and safety of a novel brain [transcranial direct current stimulation (tDCS)] and spinal cord stimulation [trans-spinal cord direct current stimulation (tsDCS)] treatment in chronic headache.

Methods

Nine participants (3 males; aged, 40 ± 15 years) suffering from chronic daily headache, chronic tension-type headache, or chronic migraine received the combined brain and spinal cord intervention for 5 consecutive days. Stimulation was applied for a total of 40 minutes (20 minutes of tDCS followed by 20 minutes of tsDCS) at 1 mA. Pain sensitivity and headache symptoms (frequency, severity, duration, and medications recorded via a headache diary, 4 weeks before and after treatment) were assessed.

Results

The treatment was safe, feasible, and well tolerated. Headache frequency was reduced following the treatment (p = 0.026) in chronic tension-type headache and chronic migraine, but not in chronic daily headache. Headache severity was reduced immediately post-treatment in 67% of sessions. A trend towards a reduction in medication use was observed (p = 0.075). No changes in headache severity (p = 0.16) or duration (p = 0.34) were present.

Conclusion

These data suggest that combined tDCS and tsDCS intervention is safe and feasible, and may improve headache frequency in patients with chronic primary headache disorders.

Abstract Image

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经颅和脊髓联合直流电刺激治疗慢性头痛:一种新型干预措施的可行性和安全性试验

慢性原发性头痛疾病与频繁、严重的疼痛和显著的功能损害相关，治疗仍然具有挑战性。目的探讨经颅直流电刺激(tDCS)和脊髓直流电刺激(tsDCS)治疗慢性头痛的可行性和安全性。方法9例受试者(男性3例;年龄(40±15岁)，慢性日常性头痛、慢性紧张性头痛、慢性偏头痛患者，连续5天接受脑脊髓联合干预。在1ma下，共进行了40分钟的刺激(20分钟的tDCS，然后是20分钟的tsDCS)。评估疼痛敏感性和头痛症状(治疗前后4周通过头痛日记记录的频率、严重程度、持续时间和用药情况)。结果治疗安全、可行、耐受性好。治疗后，慢性紧张性头痛和慢性偏头痛的头痛频率降低(p = 0.026)，而慢性日常头痛则没有减少。67%的疗程后头痛严重程度立即减轻。用药有减少的趋势(p = 0.075)。头痛严重程度(p = 0.16)和持续时间(p = 0.34)均无变化。结论tDCS与tsDCS联合干预是安全可行的，可改善慢性原发性头痛疾病患者的头痛频率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Hong Kong Physiotherapy Journal REHABILITATION-

CiteScore

2.30

自引率

6.70%

发文量

审稿时长

24 weeks

期刊介绍： The Hong Kong Physiotherapy Journal is the official journal of the Hong Kong Physiotherapy Association Limited (HKPA Ltd). This peer-reviewed journal aims to contribute to and document the advancements in the principles and practice of physiotherapy in Hong Kong.The Hong Kong Physiotherapy Journal is published annually and papers are categorized into research reports, treatment reports, technical reports, literature reviews, and letters to the editor.