Tonsil histopathology in HIV-infected versus HIV-uninfected adults.

IF 1.6 4区医学 Q4 INFECTIOUS DISEASES

Southern African Journal of Hiv Medicine Pub Date : 2019-05-28 eCollection Date: 2019-01-01 DOI:10.4102/sajhivmed.v20i1.936

Ridwaan Essa, Shivesh Maharaj, Kapila Hari, Shahpar Motakef

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引用次数: 0

Abstract

Background: The relationship between HIV and tonsil malignancy has not been fully investigated and established. Both of these diseases prominently feature in the Otorhinolaryngology clinics.

Objective: There is minimal data available on the histopathology of tonsillectomy specimens in the HIV-infected population. This retrospective review compared tonsil histopathology between HIV-infected and HIV-uninfected patients.

Methods: Of the 319 adult patients undergoing tonsillectomy (01 July 2005 to 30 June 2015), HIV results were available for 160. The histological findings were compared in the HIV-infected and HIV-uninfected subgroups. The effects of age, HIV status and CD4 count on the risk of malignancy were determined.

Results: There were 86 patients who were HIV-infected and 74 were uninfected. Reactive lymphoid hyperplasia was the most common diagnosis in both groups (77%). Malignancies were diagnosed in eight HIV-infected and six HIV-uninfected patients, an insignificant difference.

Conclusion: The majority of patients undergoing tonsillectomy had benign conditions. HIV status does not appear to be a specific risk factor for tonsil malignancies, but advanced age may be.

Abstract Image

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HIV感染者与未感染者的扁桃体组织病理学。

背景：艾滋病毒与扁桃体恶性肿瘤之间的关系尚未得到充分的调查和确定。这两种疾病都是耳鼻喉科诊所的显著特征。目的：关于HIV感染人群扁桃体切除标本的组织病理学数据很少。这篇回顾性综述比较了HIV感染和未感染患者的扁桃体组织病理学。方法：在319名接受扁桃体切除术的成年患者（2005年7月1日至2015年6月30日）中，160人获得了HIV结果。比较了HIV感染者和未感染者亚组的组织学结果。确定年龄、HIV状态和CD4计数对恶性肿瘤风险的影响。结果：86例患者为HIV感染者，74例为未感染者。反应性淋巴增生是两组中最常见的诊断（77%）。在8名艾滋病毒感染者和6名未感染者中诊断出恶性肿瘤，差异不显著。结论：大多数接受扁桃体切除术的患者病情良好。艾滋病毒状况似乎不是扁桃体恶性肿瘤的特定危险因素，但高龄可能是。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Southern African Journal of Hiv Medicine 医学-病毒学

CiteScore

2.80

自引率

11.80%

发文量

审稿时长

>12 weeks

期刊介绍： The Southern African Journal of HIV Medicine is focused on HIV/AIDS treatment, prevention and related topics relevant to clinical and public health practice. The purpose of the journal is to disseminate original research results and to support high-level learning related to HIV Medicine. It publishes original research articles, editorials, case reports/case series, reviews of state-of-the-art clinical practice, and correspondence.