Motor Cortex Function in Fibromyalgia: A Study by Functional Near-Infrared Spectroscopy.

Q2 Medicine

Pain Research and Treatment Pub Date : 2019-01-16 eCollection Date: 2019-01-01 DOI:10.1155/2019/2623161

Eleonora Gentile, Katia Ricci, Marianna Delussi, Filippo Brighina, Marina de Tommaso

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Abstract

Previous studies indicated changes of motor cortex excitability in fibromyalgia (FM) patients and the positive results of transcranial stimulation techniques. The present study aimed to explore the metabolism of motor cortex in FM patients, in resting state and during slow and fast finger tapping, using functional Near-Infrared Spectroscopy (fNIRS), an optical method which detects in real time the metabolism changes in the cortical tissue. We studied 24 FM patients and 24 healthy subjects. We found a significant slowness of motor speed in FM patients compared to controls. During resting state and slow movement conditions, the metabolism of the motor areas was similar between groups. The oxyhemoglobin concentrations were significantly lower in patients than in control group during the fast movement task. This abnormality was independent from FM severity and duration. The activation of motor cortex areas is dysfunctional in FM patients, thus supporting the rationale for the therapeutic role of motor cortex modulation in this disabling disorder.

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纤维肌痛的运动皮层功能：功能性近红外光谱研究。

以往的研究表明，纤维肌痛（FM）患者的运动皮层兴奋性发生了变化，经颅刺激技术也取得了积极的效果。功能性近红外光谱仪（fNIRS）是一种实时检测大脑皮层组织新陈代谢变化的光学方法，本研究旨在探索 FM 患者在静息状态以及手指慢速和快速敲击时运动皮层的新陈代谢情况。我们对 24 名调频患者和 24 名健康人进行了研究。我们发现，与对照组相比，FM 患者的运动速度明显减慢。在静止状态和慢速运动条件下，各组运动区的新陈代谢情况相似。在快速运动任务中，患者的氧合血红蛋白浓度明显低于对照组。这种异常与 FM 的严重程度和持续时间无关。FM 患者运动皮层区域的激活功能失调，从而支持了运动皮层调节在这种致残性疾病中的治疗作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pain Research and Treatment Medicine-Anesthesiology and Pain Medicine

CiteScore

3.60

自引率

0.00%

发文量