[Japanese Biobanks: Current Status, Problems, and Future Challenges].

Eisaburo Sueoka
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引用次数: 0

Abstract

A biobank is a facility that collects and manages biological specimens such as tissues, cells, and blood de- rived from living organisms. In addition to these materials, the biobank can also be used for storing urine, body fluid, DNA, and intracellular structures like exosomes. The initial objective of stocking these materials was mainly for research purposes, such as searching for biomarkers and genes responsible for diseases, but due to the rapid clinical application of molecular-targeted therapy and personalized medicine based on genetic information, biobanking is now becoming one of the fundamental efforts indispensable for clinical practice. In Japan, the importance of stocks of biological samples has been recognized for a long time, and biobanking was implemented in various medical institutions alone or in several medical departments, but recently the organization of biobanks has been developed and they are carrying out activities according to each purpose. 1. Biobank as a national project Biobank, Japan 2. National Center Biobank Network NCBN 3. Biobanks operated by each institution other than those mentioned above As a part of Japan's research strategy, the Japan Agency for Medical Research and Development (AMED) has promoted the "Genomic medicine realization project", and the construction of medical biobanks is one of the major projects in the strategy. In this special issue, the current status of biobanks is introduced and problems and future challenges as a national project are discussed.

[日本生物银行:现状、问题和未来挑战]。
生物库是一种收集和管理生物标本的设施,如从活生物体中提取的组织、细胞和血液。除了这些材料外,生物库还可用于储存尿液、体液、DNA和细胞内结构(如外泌体)。储存这些材料的最初目的主要是为了研究目的,例如寻找与疾病有关的生物标志物和基因,但由于基于遗传信息的分子靶向治疗和个性化医疗的快速临床应用,生物银行现已成为临床实践不可或缺的基础工作之一。在日本,长期以来人们一直认识到生物样本储存的重要性,生物银行仅在各个医疗机构或几个医疗部门实施,但最近生物银行的组织得到了发展,并根据各自的目的开展活动。1. Biobank作为国家项目Biobank,日本国家中心生物库网络ncbn3。作为日本研究战略的一部分,日本医学研究开发机构(AMED)推动了“基因组医学实现项目”,医学生物库的建设是该战略的主要项目之一。在这期特刊中,介绍了生物银行的现状,并讨论了作为国家项目存在的问题和未来的挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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