[Dynamic Visible Microcirculation and Activating Blood Removing Stasis Research].

Abstract

The technology of dynamic visualization microcirculation is to observe changes of mi- crocirculation by using visualization technology, combined with fluorescence labeling, high-speed video, electronic microscopy and other methods, converting rest images into dynamic visual graphics. In the past ten years, domestic researchers used this technology, and carried out researches on the heart, piamater/mesenteric microcirculation, dynamically observed effects of activating blood removing stasis (ABRS) research monomer, single herb and compound on arteriole/venula diameter, and the velocity of red blood cell, white blood cell adhesion, platelet aggregation, microvascular permeability, superoxide production, and plasma albumin leakage, etc. Microcirculation detection technologies were further opti- mized. Exerting direct advantages of dynamic visualization microcirculation, systematically evaluating ac- tion mechanism of Chinese herbs (multi-sites and multi-targets) , and interaction mechonism between Chinese herbs and Western drugs are important directions for future researches on microcirculation.