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Share and share alike: the role of Tra1 from the SAGA and NuA4 coactivator complexes.

IF 3.6 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Transcription-Austin Pub Date : 2019-02-01 Epub Date: 2018-10-30 DOI:10.1080/21541264.2018.1530936
Alan C M Cheung, Luis Miguel Díaz-Santín
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引用次数: 15

Abstract

SAGA and NuA4 are coactivator complexes required for transcription on chromatin. Although they contain different enzymatic and biochemical activities, both contain the large Tra1 subunit. Recent electron microscopy studies have resolved the complete structure of Tra1 and its integration in SAGA/NuA4, providing important insight into Tra1 function.

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分享和分享相似：来自SAGA和NuA4共激活子复合物的Tra1的作用。
SAGA和NuA4是染色质上转录所需的共激活子复合体。尽管它们含有不同的酶活性和生物化学活性，但都含有大的Tra1亚基。最近的电子显微镜研究已经解决了Tra1的完整结构及其在SAGA/NuA4中的整合，为Tra1的功能提供了重要的见解。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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来源期刊
Transcription-Austin
Transcription-Austin BIOCHEMISTRY & MOLECULAR BIOLOGY-
CiteScore
6.50
自引率
5.60%
发文量
9
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