Scabies mimicking graft versus host disease in a hematopoietic cell transplant recipient.

Korean Journal of Pediatrics Pub Date : 2018-11-01 Epub Date: 2018-11-09 DOI:10.3345/kjp.2018.07199
Dongsub Kim, Soo-Han Choi, Dong Youn Lee, Juyoun Kim, Eunjoo Cho, Keon Hee Yoo, Hong Hoe Koo, Yae-Jean Kim
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引用次数: 3

Abstract

Scabies is a highly contagious skin infestation caused by the mite, Sarcoptes scabiei var. hominis. Complex responses to scabies mites in the innate, humoral, and cellular immune systems can cause skin inflammation and pruritus. Diagnosis can be challenging because scabies resembles other common skin conditions. We report the first Korean case of scabies in a hematopoietic cell transplant (HCT) recipient, initially suspected of skin graft versus host disease (GVHD). A T-cell acute lymphocytic leukemia patient underwent a sibling-matched allogeneic HCT and developed pruritus after cell engraftment. Treatment for GVHD did not improve the symptoms. He was diagnosed with scabies 30 days after the onset of symptoms.

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造血细胞移植受者的疥疮模拟移植物抗宿主病。
疥疮是一种高度传染性的皮肤感染,由疥螨引起。先天、体液和细胞免疫系统对疥螨的复杂反应可引起皮肤炎症和瘙痒。诊断可能具有挑战性,因为疥疮类似于其他常见的皮肤状况。我们报告了韩国首例造血细胞移植(HCT)受者的疥疮,最初怀疑是皮肤移植物抗宿主病(GVHD)。一名t细胞急性淋巴细胞白血病患者接受了兄弟姐妹匹配的同种异体HCT,并在细胞植入后出现瘙痒。GVHD的治疗并没有改善症状。他在出现症状30天后被诊断患有疥疮。
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来源期刊
自引率
0.00%
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0
审稿时长
12 weeks
期刊介绍: Korean J Pediatr covers clinical and research works relevant to all aspects of child healthcare. The journal aims to serve pediatricians through the prompt publication of significant advances in any field of pediatrics and to rapidly disseminate recently updated knowledge to the public. Additionally, it will initiate dynamic, international, academic discussions concerning the major topics related to pediatrics. Manuscripts are categorized as review articles, original articles, and case reports. Areas of specific interest include: Growth and development, Neonatology, Pediatric neurology, Pediatric nephrology, Pediatric endocrinology, Pediatric cardiology, Pediatric allergy, Pediatric pulmonology, Pediatric infectious diseases, Pediatric immunology, Pediatric hemato-oncology, Pediatric gastroenterology, Nutrition, Human genetics, Metabolic diseases, Adolescence medicine, General pediatrics.
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