Chromosomal aberrations induced by the restriction endonucleases Alu I and Bam HI: Comparison with X-rays.

Abstract

Dose-effect relationships for the frequencies of polycentric chromosomes inducedby the restriction endonucleases Alu I and Bam HI and by X-rays in Chinese hamster ovary (CHO) cells were analyzed and compared. 1 Gy of X-rays produce the same frequency of polycentric chromosomes as 2 units Alu I and 7.9 units Bam HI.