The roles of NANOG in tumorigenesis.

Molecular & cellular oncology Pub Date : 2015-07-29 eCollection Date: 2018-01-01 DOI:10.1080/23723556.2015.1074334
Jinchul Kim, Stefan Yu, Yang Xu
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引用次数: 1

Abstract

The pluripotency factor Nanog is highly expressed in pluripotent stem cells and certain adult stem cells, but is not expressed in normal adult cells. However, Nanog is frequently overexpressed in human cancers. Here, we discuss the distinct oncogenic roles of Nanog at various stages of tumorigenesis.

NANOG在肿瘤发生中的作用。
多能因子Nanog在多能干细胞和某些成体干细胞中高表达,但在正常成体细胞中不表达。然而,Nanog在人类癌症中经常过度表达。在这里,我们讨论Nanog在肿瘤发生的不同阶段的独特致癌作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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