Apathy in Preclinical Alzheimer's Disease: Psychometric Validation of the Apathy Evaluation Scale.

IF 2.7 4区 医学 Q2 CLINICAL NEUROLOGY
Emre Umucu, Mary Wyman, Beatrice Lee, Megan Zuelsdorff, Susan Flowers Benton, Naomi Nystrom, Sterling C Johnson, Cynthia M Carlsson, Sanjay Asthana, Carey E Gleason
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引用次数: 8

Abstract

Objectives: The purpose of the present study was to validate the Apathy Evaluation Scale, self-rated version (AES-S), and assess the severity of apathy in a cognitively healthy middle-aged cohort at risk for Alzheimer’s disease (AD). Method: Three hundred and sixteen middle-aged adults were selected to represent a subset of the Wisconsin Alzheimer’s Disease Research Center Clinical Core: the Investigating Memory in People At-risk, Causes and Treatments cohort. Results: An exploratory factor analysis (EFA) with varimax rotation identified 3 subscales: apathy, disinterest, and social withdrawal factors. Confirmatory factor analysis confirmed the EFA findings. Results indicated acceptable convergent and discriminant validity. The AES-S is a reliable instrument to quantify apathy in cognitively healthy middle-aged individuals at risk for AD. Discussion: This study demonstrates the AES-S is a psychometrically sound measurement tool for assessing levels of apathy in a cognitively healthy middle-aged cohort at risk for AD.

Abstract Image

临床前阿尔茨海默病的冷漠:冷漠评估量表的心理计量学验证。
目的:本研究的目的是验证冷漠评估量表,自评版(AES-S),并评估认知健康的中年阿尔茨海默病(AD)风险队列的冷漠严重程度。方法:选择316名中年人作为威斯康星阿尔茨海默病研究中心临床核心的一个子集:调查高危人群的记忆,原因和治疗队列。结果:探索性因子分析(EFA)与可变旋转确定了3个亚量表:冷漠,无兴趣和社会退缩因素。验证性因素分析证实了EFA的发现。结果表明,收敛效度和判别效度均可接受。AES-S是一种可靠的工具来量化认知健康的中年阿尔茨海默病风险个体的冷漠。讨论:本研究表明,AES-S是一种心理测量学上可靠的测量工具,可用于评估认知健康的中年AD风险人群的冷漠水平。
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来源期刊
American Journal of Alzheimers Disease and Other Dementias
American Journal of Alzheimers Disease and Other Dementias GERIATRICS & GERONTOLOGY-CLINICAL NEUROLOGY
CiteScore
5.40
自引率
0.00%
发文量
30
审稿时长
6-12 weeks
期刊介绍: American Journal of Alzheimer''s Disease and other Dementias® (AJADD) is for professionals on the frontlines of Alzheimer''s care, dementia, and clinical depression--especially physicians, nurses, psychiatrists, administrators, and other healthcare specialists who manage patients with dementias and their families. This journal is a member of the Committee on Publication Ethics (COPE).
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