Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke.

IF 1.8 Q3 PERIPHERAL VASCULAR DISEASE
Stroke Research and Treatment Pub Date : 2018-07-02 eCollection Date: 2018-01-01 DOI:10.1155/2018/6580178
Payam Saadat, Alijan Ahmadi Ahangar, Mansor Babaei, Mandana Kalantar, Mohammad Ali Bayani, Hiva Barzegar, Hemmat Gholinia, Farbod Zahedi Tajrishi, Sekineh Faraji, Fatemeh Frajzadeh
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引用次数: 9

Abstract

Introduction: Stroke is one of the most common neurological disorders with high mortality rates. A large financial burden is imposed on the families and health systems of countries in addition to the problems related to the disabilities caused by the disease for the patients. Extensive research is being conducted on the disease, including studies seeking possible relationships between some biomarkers such as uric acid and stroke.

Methods: This descriptive-analytic cross-sectional study was conducted on 170 stroke patients at Babol Ayatollah Rohani Hospital during 2015-2016. Serum uric acid (SUA) levels were measured and recorded at admission time. Patients' demographic data as well as the stroke type and some of their risk factors were entered in a checklist. The data were analyzed by SPSS.v.23 using chi-square and logistic regression tests. P < 0.05 was considered as significant in all analyses.

Results: Of the total 170 included patients, 57% had normal, 25% had low, and the remaining patients (18%) had high SUA levels. There was no significant difference in SUA levels in different types of stroke in both genders. Diabetic ischemic embolic patients had higher levels of SUA than diabetic ischemic thrombotic cases. Patients with low magnesium levels had higher rate of low levels of SUA in ischemic stroke.

Conclusion: Serum uric acid levels are not associated with stroke types and gender. Diabetic embolic ischemic stroke cases had high SUA levels than thrombotic types and in ischemic stroke patients with low serum levels of magnesium, SUA levels were also lower.

卒中患者血清尿酸水平与人口学特征、危险因素、严重程度、预后、血清维生素D、钙、镁水平的关系
脑卒中是最常见的神经系统疾病之一,死亡率高。除了与该病给患者造成残疾有关的问题外,还给各国的家庭和卫生系统造成了巨大的经济负担。人们正在对这种疾病进行广泛的研究,包括寻找一些生物标志物(如尿酸)与中风之间可能存在的关系。方法:对2015-2016年在巴博勒阿亚图拉鲁哈尼医院就诊的170例脑卒中患者进行描述性分析横断面研究。入院时测定并记录血清尿酸(SUA)水平。患者的人口统计数据以及中风类型和一些危险因素被输入到检查表中。采用SPSS.v软件对数据进行分析。23采用卡方和逻辑回归检验。所有分析均认为P < 0.05显著。结果:在170例患者中,57%为正常,25%为低水平,其余患者(18%)为高水平。不同类型脑卒中患者的SUA水平在两性中无显著差异。糖尿病缺血性栓塞患者的SUA水平高于糖尿病缺血性血栓患者。低镁血症患者缺血性脑卒中中低水平SUA发生率较高。结论:血清尿酸水平与脑卒中类型和性别无关。糖尿病栓塞性缺血性脑卒中患者的SUA水平高于血栓性脑卒中患者,血清镁水平较低的缺血性脑卒中患者的SUA水平也较低。
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来源期刊
Stroke Research and Treatment
Stroke Research and Treatment PERIPHERAL VASCULAR DISEASE-
CiteScore
3.20
自引率
0.00%
发文量
14
审稿时长
12 weeks
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