[Nitric Oxide Signaling Pathway and Vascular Activity].

生理科学进展 Pub Date : 2017-02-01

Yuan-Sheng Gao

引用次数: 0

Abstract

Nitric oxide-cyclic guanosine 3',5'-monophosphate (cGMP)-cGMP dependent protein kinase signaling pathway is a key mechanism for the modulation of vascular function. The progress in this area of recent years was briefly summarized in this article, in particular, regarding the redox-dependent dimerization of the relevant signaling molecules and their physiological significance as well as the role of soluble guanylyl cyclase-derived cyclic inosine 3',5'-monophosphate as a new messenger for vasoconstriction.

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一氧化氮信号通路与血管活性

一氧化氮-环鸟苷3′，5′-单磷酸(cGMP)-cGMP依赖性蛋白激酶信号通路是调控血管功能的关键机制。本文综述了近年来该领域的研究进展，重点介绍了相关信号分子的氧化还原依赖性二聚化及其生理意义，以及可溶性鸟酰环化酶衍生的环肌苷3′，5′-单磷酸环肌苷作为血管收缩新信使的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

生理科学进展

自引率

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5953

期刊介绍： Progress in Physiological Sciences is a bimonthly academic journal co-sponsored by Chinese Association for Science and Technology, Chinese Physiological Society and Peking University. It was founded in March 1957. China Core Journal of Science and Technology, China Core Journal of Medicine and Health, Statistical source journal of Chinese Academic Journal Impact Factor Annual Report, China Science Citation Database CSCD (1996-2018); Overview of Key Chinese Core Journals of Peking University (1992-2020, 2023-), It has been reported by China Journal Network, China Academic Journals (Optical Disc Edition), China Biomedical Citation Database CMCI, Science and Technology Journals World Impact Index (WJCI) (2022), Wanfang Data Resource System digital Journal Group (China Core Journal Database); American Medical Index (IM), American Chemical Abstracts (CA), etc. Progress in Physiological Sciences is published at home and abroad. The journal comprehensively reports the new progress in physiological sciences at home and abroad, and publishes review papers related to physiological sciences, namely physiology, biochemistry and molecular biology, pharmacology, pathophysiology, biophysics, nutrition, etc.