Mustafa Kaplan, Ihsan Ates, Mahmut Yuksel, Mehmet F Arikan, Gulden Aydog, Nesrin Turhan, Volkan Gökbulut, Ertugrul Kayacetin
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引用次数: 9
Abstract
Background/aim: The aim of this study was to investigate the role of the platelet-to-lymphocyte ratio (PLR)-neutrophil-to-lymphocyte ratio (NLR) combination, in the prediction of the presence of Helicobacter pylori (HP) and its associated complications in the gastrointestinal system.
Patients and methods: In all, 1289 patients who underwent esophagogastroduodenoscopy and biopsy for HP were included in the study.
Results: The ratio of patients with moderate and severe chronic gastritis was higher in HP (+) group than HP (-) group. The ratio of patients with levels 1-3 atrophy and intestinal metaplasia was higher in HP (+) group. Compared with HP (-) group, HP (+) had higher PLR and NLR levels. The ratio of HP (+) patients was higher in high-risk group compared with low- and medium-risk groups. HP invasion stage, the intestinal metaplasia level, and the ratio of patients with atrophy level "3" were higher in high-risk group compared with low- and medium-risk groups. Regression analysis showed that the PLR-NLR combination was an independent risk factor for both HP presence and moderate and severe chronic gastritis.
Conclusion: We found the PLR-NLR combination to be a good predictor of HP presence and gastrointestinal complications associated with HP.
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